The rate of rise of intraventricular pressure as an index of myocardial contractility in conscious and anaesthetised ponies

Hillidge, C.J.; Lees, P.

doi:10.1016/s0034-5288(18)33369-1

Cited by 10 publications

(4 citation statements)

References 23 publications

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“…Some of these have been used to assess the contractile state of the equine myocardium (Sporri and Denac, 1969;Hillidge and Lees, 1976;Buss and Bisgard, 1976). Some of these have been used to assess the contractile state of the equine myocardium (Sporri and Denac, 1969;Hillidge and Lees, 1976;Buss and Bisgard, 1976).…”

mentioning

confidence: 99%

“…Accepting that a simple index is unlikely to reveal all the information about the contracting heart, several have been devised which are based on the first and higher derivatives of the ventricular pressure pulse. Some of these have been used to assess the contractile state of the equine myocardium (Sporri and Denac, 1969;Hillidge and Lees, 1976;Buss and Bisgard, 1976). Taylor (1970) gave the theoretical basis of some of them and related them to the basic concepts of muscle mechanics.…”

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Assessment of Myocardial Function in the Horse 1. Theoretical and Technical Considerations

Brown

Holmes

1979

Equine Veterinary Journal

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SUMMARY The paper discusses the various parameters which are currently used in attempts to assess the contractile efficiency of the myocardium in various species. These procedures depend upon accurate recording of intracavity pressure. The response of a catheter‐mounted microtransducer compared with a fluid‐filled catheter manometer system is illustrated to show the advantage of the former in providing a true representation of pressure changes. RÉSUMÉ Cet article passe en revue les différents paramětres qui sont retenus pour apprécier l'aptitude du myocarde à se contracter dans des espèces différentes. Ces procédés reposent sur la mesure precise de la pression intracardiaque. Les RÉSultats obtenus avec un catheter équipé d'un micro enregistreur, sont compaRÉS avec ceux obtenus à l'aide d'un catheter équipé d'un manomètre à fluide. Le premier appareillage donne une meilleure repRÉSentation des variations de pression. ZUSAMMENFASSUNG Dieser Artikel diskutiert die verschiedenen Parameter, die zur Zeit verwendet werden zur Beurteilung der Kontraktionskraft des Myocards bei verschiedenen Tierarten, Diese Methoden hängen ab von einer genauen Feststellung des Drucks in den Herzhöhlen. Es wird gezeigt, dass sich ein auf dem Herzkatheter montierter Mikro‐transducer besser eignet zur Erzielung genauer Messengen von Druckveränderungen als ein flüssigkeitgefülltes Katheter‐Manometersystem.

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confidence: 99%

mentioning

confidence: 99%

Assessment of Myocardial Function in the Horse 1. Theoretical and Technical Considerations

Brown

Holmes

1979

Equine Veterinary Journal

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“…Nesse sentido, deve-se ressaltar que, neste estudo, os valores médios da resistência vascular periférica total e do índice da resistência periférica total, em ambos os grupos, permaneceram estáveis. A anestesia pelo halotano reduziu o débito cardíaco, a fração de encurtamento e de ejeção, fato este determinado, provavelmente, pelo efeito inotrópico negativo desse anestésico (HILLIDGE & LEES, 1976).…”

Section: Resultsunclassified

Efeitos Da Infusão Contínua De Cetamina S(+) Em Eqüinos Anestesiados Pelo Halotano

et al. 2010

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sérgio patto dos santos 3 e Carlos augusto arauJo valadão 4 1. Pós-graduando do Programa de Cirurgia Veterinária da FCAV UNESP 2. Professor adjunto do DCCV/FCAV UNESP 3. Professor doutor do Departamento de Clínica, Cirurgia e Reprodução Animal do Curso de Medicina Veterinária da FOA UNESP 4. Professor titular do DCCV/FCAV UNESP. RESUMOA manutenção da pressão arterial, no transanestésico, consiste grande desafio, principalmente quando se trata da espécie equina, suscetível à instabilidade cardiovascular. Por isso, torna-se imperioso utilizar técnica anestésica que mantenham estáveis os parâmetros cardiovasculares. A cetamina tem sido amplamente empregada na indução anestésica para o halotano em equinos, conferindo-lhes estabilidade cardiovascular. A cetamina S(+), recentemente disponibilizada no mercado, induz estimulação cardiovascular e possui maior potência anestésica e analgésica em relação à cetamina. Todavia, os efeitos dessa substância, admi-nistrada por infusão contínua durante a manutenção da anestesia pelo halotano em equinos, ainda não foram avaliados. Em face da tendência atual de a infusão continuada da cetamina potencializar os anestésicos inalatórios, considerou-se pertinente avaliar os efeitos cardiovasculares e respiratórios desse isômero de cetamina em equinos anestesiados pelo halotano. Conclui-se que a infusão contínua de 0,01mg/kg/min de cetamina S(+) durante anestesia com 1,5 CAM de halotano em equinos não agravou a depressão cardiorrespiratória promovida por esse anestésico inalatório. PALAVRAS-CHAVES: Cetamina S(+), equinos, halotano, infusão contínua.

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“…These basal HR and BP measurements were within the range of values published previously for adult ponies and other small equine breeds using non-invasive methods or short-term percutaneous catheterisation. [41][42][43][44][45] Hypertensive challenge: cardiovascular responses to PE…”

Section: Basal Cardiovascular Measurementsmentioning

confidence: 99%

Neonatal glucocorticoid overexposure alters cardiovascular function in young adult horses in a sex-linked manner

Valenzuela

Jellyman

Allen

et al. 2020

J Dev Orig Health Dis

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Prenatal glucocorticoid overexposure has been shown to programme adult cardiovascular function in a range of species, but much less is known about the long-term effects of neonatal glucocorticoid overexposure. In horses, prenatal maturation of the hypothalamus–pituitary–adrenal axis and the normal prepartum surge in fetal cortisol occur late in gestation compared to other precocious species. Cortisol levels continue to rise in the hours after birth of full-term foals and increase further in the subsequent days in premature, dysmature and maladapted foals. Thus, this study examined the adult cardiovascular consequences of neonatal cortisol overexposure induced by adrenocorticotropic hormone administration to full-term male and female pony foals. After catheterisation at 2–3 years of age, basal arterial blood pressures (BP) and heart rate were measured together with the responses to phenylephrine (PE) and sodium nitroprusside (SNP). These data were used to assess cardiac baroreflex sensitivity. Neonatal cortisol overexposure reduced both the pressor and bradycardic responses to PE in the young adult males, but not females. It also enhanced the initial hypotensive response to SNP, slowed recovery of BP after infusion and reduced the gain of the cardiac baroreflex in the females, but not males. Basal diastolic pressure and cardiac baroreflex sensitivity also differed with sex, irrespective of neonatal treatment. The results show that there is a window of susceptibility for glucocorticoid programming during the immediate neonatal period that alters cardiovascular function in young adult horses in a sex-linked manner.

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The rate of rise of intraventricular pressure as an index of myocardial contractility in conscious and anaesthetised ponies

Cited by 10 publications

References 23 publications

Assessment of Myocardial Function in the Horse 1. Theoretical and Technical Considerations

Assessment of Myocardial Function in the Horse 1. Theoretical and Technical Considerations

Efeitos Da Infusão Contínua De Cetamina S(+) Em Eqüinos Anestesiados Pelo Halotano

Neonatal glucocorticoid overexposure alters cardiovascular function in young adult horses in a sex-linked manner

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