The regulatory effects of fucoidan and laminarin on functional dyspepsia mice induced by loperamide

Abstract

Gastrointestinal dysmotility is a common cause of functional dyspepsia. Fucoidan and laminarin possess many physiological properties, however, their relative abilities in regulating gastrointestinal motility have not been illustrated yet. In...

Integrated metabolomics and transcriptomics revealed the anti-constipation mechanisms of xylooligosaccharides from corn cobs

“…Acetylcholine, a vital neurotransmitter for many bodily and mental functions, could stimulate the smooth muscles in the gastrointestinal tract and promote the coordinated movement of the gastric antrum and duodenum. 32 According to a recent study, proteomic analysis revealed that Moringa oleifera's action in reducing constipation involved acetylcholine receptor-mediated pathways. 33 Several literatures indicated that the elevated levels of ET-1 and NO caused tissue damage and exacerbated inflammation.…”

From algae to advancements: laminarin in biomedicine

“…Moreover, the intervention with laminarin had a prominent impact on the composition of the gut microbiota, which involves alterations in the abundance of various species, such as Muribaculaceae, Lachnospiraceae, and Streptococcus. 90 The connection between the abundance of these species and their role in the modulating of gastrointestinal motility is still unclear. Speculations concerning the functions of these bacteria remain hypothetical and should be conrmed through further experiments in the future.…”