The relations between long-latency reflexes in hand muscles, somatosensory evoked potentials and transcranial stimulation of motor tracts

Deuschl, Günther; Ludolph, Albert C.; Schenck, E.; Lücking, Carl Hermann

doi:10.1016/0168-5597(89)90031-2

Cited by 55 publications

(33 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found a similar 10 ms delay between the latency of the somatosensoryevoked potential and the onset of the facilitation of the cortically evoked responses by the cutaneous stimuli (see below), again suggesting a delay of approximately 10 ms between the arrival of the cutaneous volley at the level of the cortex and its effect on the motor output. Deuschl, Ludolph, Schenck & L ucking (1989) similarly found that transcortical reflexes from digital nerves in the hand required approximately 8-10 ms for central processing. A similar type of reasoning has also been used by Burke et al (1991) to exclude a supraspinal mechanism for the earlier occurring effects in the TA following Su stimulation.…”

Section: Discussionmentioning

confidence: 82%

Evidence Suggesting a Transcortical Pathway from Cutaneous Foot Afferents to Tibialis Anterior Motoneurones in Man

Nielsen

Petersen

Fedirchuk

1997

The Journal of Physiology

135

View full text Add to dashboard Cite

Stimulation of the superficial peroneal or the sural nerve (3 shocks, 3 ms interval, 1 ms duration, 2.5 × perception threshold) evoked a reflex activation of the tibialis anterior muscle at a latency of approximately 70–95 ms in all of nine healthy human subjects. Stimulation of the medial plantar nerve only rarely produced similar effects. The possibility that a transcortical pathway contributes to these late reflex responses was investigated by combining the cutaneous stimulations and a transcranial magnetic stimulation of the contralateral motor cortex. A significant facilitation of short‐latency peaks in the post‐stimulus time histogram of single tibialis anterior motor units evoked by the transcortical magnetic stimulation was observed in eight out of nine subjects following stimulation of the superficial peroneal or sural nerves at the latency of the long‐latency reflex. In contrast such a facilitation was only rarely seen when the medial plantar nerve was stimulated. With the same timing for the stimuli, the superficial peroneal and sural nerve stimulations also produced a significant increase in the short‐latency, presumed monosynaptic, facilitation of the tibialis anterior H reflex produced by the brain stimulation. Similar facilitatory effects of the cutaneous stimuli could not be demonstrated when the magnetic stimulation of the cortex was replaced with electrical stimulation, implying that cortical excitability is affected by a conditioning cutaneous stimulation. It is suggested that the long‐latency reflexes in the tibialis anterior muscle evoked by activation of cutaneous afferents from the human foot are, at least partly, mediated by a transcortical pathway.

show abstract

Section: Discussionmentioning

confidence: 82%

Evidence Suggesting a Transcortical Pathway from Cutaneous Foot Afferents to Tibialis Anterior Motoneurones in Man

Nielsen

Petersen

Fedirchuk

1997

The Journal of Physiology

135

View full text Add to dashboard Cite

show abstract

“…In our subjects, early MEP potentiation was present at ISI of 20 to 25 ms. It has been calculated that the minimal afferent conduction time from the digit to the cortex is approximately 23 ms, 18 and the intracortical relay time has been estimated as being 3.5 to 8 ms. 34 This means that cortical inhibition should not begin before 26.5 to 31 ms. Furthermore, in all our patients, the first cortical giant SEP components to digital stimulation had a latency ranging from 28 to 29 ms.…”

Section: Discussionmentioning

confidence: 99%

Memory fMRI lateralizes temporal lobe epilepsy

Jokeit¹,

Okujava²,

Woermann³

2001

Neurology

174

100

View full text Add to dashboard Cite

show abstract

“…In our study, CC area was not correlated with LLR parameters (latency, latency difference, amplitude, and amplitude ratio of both sides). Previous studies mostly aimed to compare LLR with other NP tests such as SEP and MEP in MS (2,15,16). In addition, the CC has been a promising candidate in various studies because of its sensitivity to demyelination and axonal loss.…”

Section: Discussionmentioning

confidence: 99%

“…Although VEP was considered to be the most useful neurophysiological test for the evaluation of MS patients in the past, there have been studies about LLR examinations in the diagnosis of MS after the early 1990s (3,(14)(15)(16)(17)(18).…”

Section: Introductionmentioning

confidence: 99%

Long-latency Reflexes and Area Measurements of Corpus Callosum in Patients with Multiple Sclerosis

Toydemir¹,

Gökyiğit²,

Seleker³

et al. 2016

Bezmialem Science

View full text Add to dashboard Cite

Objective: We aimed to establish the utility of long-latency reflex (LLR) examinations and area measurements of corpus callosum (CC) in the assessment of multiple sclerosis (MS) and determination of disability caused by axonal degeneration. Methods: This study was prospectively conducted with 23 MS patients with "definite MS" and a control group of 15 healthy individuals. Neurologic examination of the control group and MS patients were performed, and Expanded Disability Status Scale (EDSS) scores were estimated. LLR examination and callosal area measurements were performed for all individuals. Results: In the MS group, LLR latencies were longer and callosum areas were smaller than that in the control group. There were no significant correlations between CC area and latency, latency difference, or amplitude in the MS group (p=0.606, p=0.736, and p=0.757, respectively). In the MS group, we found a significant correlation between EDSS and CC area. There was a significant negative correlation between the duration of disease and corpus callosum area (p=0.016). Only patients with mild deficits were included in this study, and nearly half the patients had normal LLR tests and corpus callosum area measurements. Therefore, the probability of finding a significant correlation between them was low. These findings revealed the need for other studies that would be performed with more patients. Conclusion: Long-latency reflex examination and CC area measurements may be used together or alone for the evaluation of patients with MS and for the estimation of disability as safe and easy tests.

show abstract

The relations between long-latency reflexes in hand muscles, somatosensory evoked potentials and transcranial stimulation of motor tracts

Cited by 55 publications

References 26 publications

Evidence Suggesting a Transcortical Pathway from Cutaneous Foot Afferents to Tibialis Anterior Motoneurones in Man

Evidence Suggesting a Transcortical Pathway from Cutaneous Foot Afferents to Tibialis Anterior Motoneurones in Man

Memory fMRI lateralizes temporal lobe epilepsy

Long-latency Reflexes and Area Measurements of Corpus Callosum in Patients with Multiple Sclerosis

Contact Info

Product

Resources

About