We tested preregistered hypotheses (a) examining the structure of supernatural beliefs and perceived experiences and (b) predicting supernatural engagement from the Big Five and cognitive styles. Exploratory and confirmatory factor analysis (CFA) of self-report data in the U.S. undergraduates (Study 1: n = 1,401; Study 2: n = 1,939) showed that beliefs and perceived experiences were characterized by two factors. Positive and Negative Agents factors related strongly to religious belief salience and were defined by God, the devil, angels, demons, and ghosts/spirits, whereas Forces and Spirits factors were unrelated to religious belief salience and were defined by fate/destiny, karma, and ghosts/spirits. Extraversion, conscientiousness, experiential processing, schizotypy, and dissociative tendencies related positively to supernatural engagement. With some nuances, agreeableness, neuroticism, and need for closure were positive predictors, whereas skepticism and analytical-rational processing were negative predictors. Openness and intellectual humility did not relate positively to supernatural engagement, contradicting expectations. Because the literature on individual differences predictors of supernatural engagement is not well integrated, these results may contribute to a more comprehensive understanding of this topic.