The Relationship between Anthropometry and Ankle-Brachial Index with Blood Glucose Level in Patients with Type 2 Diabetes Mellitus at Community Health Center in Medan, Indonesia

Amelia, Rina; Burhan, Burhan; Lelo, Aznan

doi:10.5114/fmpcr.2018.79339

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…Diabetic neuropathy is one of the macrovascular complications in Type 2 DM patients; this can occur due to uncontrolled blood sugar in diabetic patients, the more uncontrolled, the faster the neuropathy complaints [1].…”

Section: Introductionmentioning

confidence: 99%

Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

Amelia¹,

Wahyuni²,

Yunanda³

2019

Open Access Maced J Med Sci

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BACKGROUND: Diabetic neuropathy is one of the most complicated complications of diabetes patients with Type 2 diabetes. AIM: The purpose of this study was to determine the diagnosis of diabetic neuropathy based on Clinical Neurological Examination (CNE) and the factors that influence the occurrence of diabetic neuropathy in Type 2 DM patients at Amplas Primary Health Care (PHC) in Medan City. METHODS: The research design was descriptive-analytic with the cross-sectional approach. The study population was all Type 2 DM patients who came to Amplas PHC with a total sample of 53 people using the consecutive sampling. The research data source is primary data, namely the assessment of diabetic neuropathy using the Clinical Neurological Examination (CNE) criteria. Data were processed using SPSS and analysis using the chi-square test. RESULTS: The results showed the majority of Type 2 DM patients had mild neuropathy as many as 24 people (45.3%). The Chi-square test results showed there was a relationship between age and duration of diabetes with the incidence of diabetic neuropathy in Type 2 DM patients at Amplas Primary Health Care. CONCLUSION: Education and early detection with proper management can prevent more severe complications so that the quality of life of patients can be maintained better.

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Section: Introductionmentioning

confidence: 99%

Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

Amelia¹,

Wahyuni²,

Yunanda³

2019

Open Access Maced J Med Sci

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“…Over time, high blood glucose levels might harm the tiny blood vessels that nourish the neurons and obstruct their ability to receive vital nutrients. As a result, the nerve fibres may sustain injury [52] that alters the neurotransmitters and neurotrophins previously mentioned. As a valid indicator of chronic glycemia and a predictor of the likelihood of long-term diabetic problems [53], HbA1c significantly correlated with NA, NGF, and BDNF in our investigation.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Body Weight Gain with or Without Diabetes Type 2 on the Levels of Noradrenalin and Some Neurotrophins

Hasan,

Jouda,

Saihood

2023

Kufa Jour. Bio.

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This work aimed to study the effect of body weight gain in individuals with or without diabetes mellitus Type 2 (DMT2) on the nervous system. Seventy-five subjects participated in this study, including 25 obese patients with DMT2 (BMI≥30kg/m2), 25 obese individuals without diabetes (BMI≥30kg/m2) and normal-weight healthy (BMI˂25kg/m2). In addition to body mass index (BMI), the west/hip ratio (WHR) and total body fat (TBF%) were calculated. 10ml of blood was collected from participants and used to determine the levels of HbA1C, noradrenaline (NA), brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and fasting blood glucose (FBG). The level of NGF increased while BDNF and NA levels decreased in obese with and without diabetes compared to control. Interestingly, BDNF level was significantly higher in the obese with diabetes than without. Moreover, TBF% and WHR values were significantly higher in the obese with diabetes when compared with those without diabetes. At the same time, there were no significant differences between BMI value in these two groups. BMI, TBF% and WHR significantly correlate with FBG, HbA1C and NGF and negative significant correlation with BDNFdoes not correlate; only WHR has no correlationdoes and does not correlate with NA. As well as, HbA1C has a significant correlation with the nerve markers, positive with BDNF and NGF and negative with NA, while FBG did not correlate with them. In conclusion, neurotransmitters and neurotrophin levels could use as risk factors for diabetes, and obesity could be considered as a risk factor for neuropathy as much as diabetes.

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Prevalence, Characteristics and Risk Factors Analysis of Prediabetes: A Cross-Sectional Study

Amelia,

Harahap,

Wijaya

et al. 2024

F1000Res

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Background Prediabetes, a reversible condition before the onset of diabetes, is a significant concern in healthcare globally. The global prediabetes epidemic has emerged and has considerably impacted health expenditures. Various risk factors play important roles in the progression of prediabetes to diabetes. Intensive lifestyle and pharmacological interventions can significantly reduce the risk of diabetes progression. Objective This study aimed to determine the prevalence, characteristics, and risk factors of prediabetes state of Medan in August 2023. Methods The sample consisted of 89 participants. This was an analytical cross-sectional study in the community that met the inclusion and exclusion criteria. The determination of prediabetes is based on the results of blood tests, namely, the examination of fasting blood sugar levels (FBGL), 2-hour postprandial oral glucose tolerance test (OGTT), and hemoglobin A1c (HbA1C). Other examinations included lipid profiling (total cholesterol, HDL-C, LDL-C, and triglycerides). Data processing was performed using SPSS via univariate and bivariate analyses (chi-square test). Results Of the 89 participants, the prevalence of prediabetes based on HbA1c, FBGL and 2-hours OGTT levels was 28.1%, 50.6%, and 28.1%, respectively. 82% of the participants were female, and 53.9% were overweight or obese based on body mass index (BMI). The risk factors related to the prevalence of prediabetes were HbA1c level, impaired FBGL, and impaired 2-hours OGTT. Other risk factors such as age, sex, daily exercise, diet, BMI, waist-hip ratio, acanthosis nigricans, lipid profile, and blood pressure did not correlate significantly with the risk factors (p>0.05). Conclusion This study found that the prevalence of prediabetes was 67.4% in Medan, 82% of the participants were female, and more than 50% of participants were overweight or obese. HbA1c, FBGL, and 2-hour postprandial OGTT were the most important risk factors for prediabetes.

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The Relationship between Anthropometry and Ankle-Brachial Index with Blood Glucose Level in Patients with Type 2 Diabetes Mellitus at Community Health Center in Medan, Indonesia

Cited by 4 publications

References 18 publications

Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients at Amplas Primary Health Care in Medan City

The Effect of Body Weight Gain with or Without Diabetes Type 2 on the Levels of Noradrenalin and Some Neurotrophins

Prevalence, Characteristics and Risk Factors Analysis of Prediabetes: A Cross-Sectional Study

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