The Relationship between Circulating Antibodies and Immunity to Helminthic Infections

Phlyctenular eye disease in association with Hymenolepis nana in Egypt.

“…As the parasite is not restricted to the gut, the degree to which it comes into contact with tissue fluids and serum of the host is increased. The development of helminths from the embryonic and larval stages to the sexually mature forms must include biochemical and physiological changes, all of which make the antigenic mosaic increasingly complex (Sinclair, 1970). Several workers have shown that different stages of the worms can elicit different types of antibodies in the host which are to some degree stage-specific, but it is also known that, at least for some helminths, 1 stage is as efficient as another in stimulating immune bodies.…”

“…Several workers have shown that different stages of the worms can elicit different types of antibodies in the host which are to some degree stage-specific, but it is also known that, at least for some helminths, 1 stage is as efficient as another in stimulating immune bodies. Sinclair (1970) stated that little is known about enzymes which might help the parasite in its invasion of the host tissue, and consequently even less is known about the antibodies which these might stimulate. However, Bogitsh (1967) demonstrated esterases and an alkaline phosphatase in H. nana cysticercoids.…”

Immunoglobin E and eosinophil levels in atopic and non‐atopic populations infested with hookworm

“…The relationship between reaginic antibodies and protective immunity in animals is (Sinclair, 1970;Kelly. 1973).…”

Immunity to Parasites

“…For more brief, specialized reviews, see Wakelin (1978) and Barriga (1981). Also, the volume edited by Soulsby (1972) and the review by Sinclair (1970) should be consulted.…”