The relationship between COVID-19 and the dental damage stage determined by radiological examination

Şirin, Dursun Ali; Özçeli̇k, Fatih

doi:10.1007/s11282-020-00497-0

Cited by 34 publications

(38 citation statements)

References 49 publications

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“…Although among the studies that clinically addressed COVID-19, the most used form of diagnosis was RT-PCR in the detection of viral RNA, the serological analysis also was used in the detection of IgG and IgM antibodies (Amorim Dos Santos et al, 2021;Amorim Dos Santos et al, 2020b;Brandao et al, 2021;Cebeci Kahraman, Ozen, et al, 2020;L. Chen et al, 2020b;Cherif et al, 2020;Cirillo et al, 2021a;Coke et al, 2021a;Cruz Tapia et al, 2020;Eghbali Zarch & Hosseinzadeh, 2021a;Elibol, 2021;Fantozzi et al, 2020;Fernandes Matuck et al, 2020;Fidan et al, 2021;Freni et al, 2020;Gherlone et al, 2021;Halboub et al, 2020;Hockova et al, 2021;Karadas et al, 2020;Kitakawa et al, 2020a;Lechien et al, 2020b;Moreira et al, 2020a;Morteza Mousavi-Hasanzadeh et al, 2020;Nitecki et al, 2021;Ramires et al, 2021;Saniasiaya et al, 2021;Sheng et al, 2021;Sirin & Ozcelik, 2021;Tham et al, 2021). Sputum and saliva analysis, nasal and throat smears were also used (Bao et al, 2020;Cherif et al, 2020;Coke et al, 2021a).…”

Section: Discussionmentioning

confidence: 99%

“…Another variable investigated by some authors was the previous health conditions of the patients who composed the samples, with systemic alterations being mentioned chronic obstructive pulmonary disease (Bao et al, 2020;Brandao et al, 2021;Elibol, 2021;Fantozzi et al, 2020;Gherlone et al, 2021;Larvin et al, 2020a;Sirin & Ozcelik, 2021), diabetes mellitus (Bao et al, 2020;Biadsee et al, 2020;Brandao et al, 2021;Chern et al, 2020;Coke et al, 2021a;Fantozzi et al, 2020;Fernandes It is worth noting that ACE2 plays an important role in blood pressure regulation. Thus, the disruption of the bloodbrain barrier can happen due to endothelial dysfunctions as a consequence of the evolution of COVID-19.…”

Section: Discussionmentioning

confidence: 99%

“…Matuck et al, 2020;Freni et al, 2020;Gherlone et al, 2021;Halboub et al, 2020;Lovato & de Filippis, 2020;Marouf et al, 2021;Ramires et al, 2021;Sirin & Ozcelik, 2021), arterial hypertension (Amorim DosSantos et al, 2021;Bao et al, 2020;Biadsee et al, 2020;Brandao et al, 2021;Chern et al, 2020;Coke et al, 2021a;Eghbali Zarch & Hosseinzadeh, 2021a;Elibol, 2021;Fantozzi et al, 2020;Fernandes Matuck et al, 2020;Freni et al, 2020;Halboub et al, 2020;Hockova et al, 2021;Larvin et al, 2020a;Lovato & de Filippis, 2020;Nitecki et al, 2021;Ramires et al, 2021;Sirin & Ozcelik, 2021), cancer(Coke et al, 2021a;Fantozzi et al, 2020;Fernandes Matuck et al, 2020;Gherlone et al, 2021;Sirin & Ozcelik, 2021), heart diseases (Amorim DosCoke et al, 2021a;Elibol, 2021;Fantozzi et al, 2020;Fernandes Matuck et al, 2020;Gherlone et al, 2021;Lovato & de Filippis, 2020;Moreira et al, 2020a), obesity(Brandao et al, 2021;Coke et al, 2021a;…”

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Oral manifestations detected in COVID-19 patients: an integrative review

Ramirez

Soares

Ramos

et al. 2021

RSD

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The aim of this integrative review consisted of verifying whether the oral manifestations detected in patients diagnosed with COVID-19 are useful in diagnosing the disease, whether they are a manifestation resulting from the disease, or whether there is evidence that there is no correlation between the pathologies. Therefore, articles in the PubMed, Lilacs, Scopus, Science Direct, Web of Science and Embase databases were searched, in addition to the search in gray literature. The terms used in the search were: “COVID-19” or “Sars-Cov-2” or “coronavirus” and “oral conditions” or “oral health” or “oral manifestations” and “diagnosis/complications” or “symptoms”. Thus, 1.305 articles were selected, of which 61 were selected to compose this review. Most of the included studies considered oral symptoms as taste changes, xerostomia and ulcerative lesions in the oral and labial mucosa. All symptoms related to this pathology still need further studies and investigations so that all mechanisms and manifestations related to it are completely elucidated.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Oral manifestations detected in COVID-19 patients: an integrative review

Ramirez

Soares

Ramos

et al. 2021

RSD

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“…MiR-2392 was also predicted to affect other diseases that have been linked to COVID-19 infection in some patients. For example, COVID-19 patients have experienced azoospermia, which is linked to male infertility (Younis et al, 2020), altered menstrual cycle in females (Li et al, 2021), dental damage (Sirin and Ozcelik, 2021), and deafness or hearing loss (Koumpa et al, 2020). Using the tool Kaplan-Meier Plotter (Győrffy, 2021) to associate miR-2392 expression with pan-cancer patient survival (Fig.…”

Section: The Impact Of Mir-2392 On Diseases Relationship To Covid-19 Symptoms and Predicted Fda Drugs To Target Mir-2392mentioning

confidence: 99%

The Great Deceiver: miR-2392’s Hidden Role in Driving SARS-CoV-2 Infection

McDonald

Enguita

Taylor

et al. 2021

Preprint

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SummaryMicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provides an exciting avenue towards antiviral therapeutics. From patient transcriptomic data, we have discovered a circulating miRNA, miR-2392, that is directly involved with SARS-CoV-2 machinery during host infection. Specifically, we found that miR-2392 was key in driving downstream suppression of mitochondrial gene expression, increasing inflammation, glycolysis, and hypoxia as well as promoting many symptoms associated with COVID-19 infection. We demonstrate miR-2392 is present in the blood and urine of COVID-19 patients tested, but not detected in COVID-19 negative patients. These findings indicate the potential for developing a novel, minimally invasive, COVID-19 detection method. Lastly, using both in vitro human and in vivo hamster models, we have developed a novel miRNA-based antiviral therapeutic targeting miR-2392 that significantly reduces SARS-CoV-2 viability and may potentially inhibit a COVID-19 disease state in the host.

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“…We would like to share ideas on the publication "The relationship betweenCOVID-19 and the dental damage stage determined by radiological examination [1]." Sirin and Ozcelik noted that "The relationship detected between dental damage (DD) stage and the severity and prognosis of viral disease such as COVID-19 was found to be remarkable for extensive studies [1]." The data on the impact of COVID-19 on dental health is limited.…”

Section: Dear Editormentioning

confidence: 99%