The Relationship Between Interatrial Block and PASI Score in Patients with Psoriasis

Abstract

The relationship between the interatrial block (IAB) and atrial fibrillation (AF) has been demonstrated in previous studies. The aim of this study is to investigate the relationship of the IAB with the psoriasis area severity index (PASI) score in psoriasis. Method: Patients with psoriasis who were examined at the cardiology outpatient clinic between January 2017 and May 2019 were retrospectively screened. Two hundred and thirty-eight patients whose electrocardiogram (ECG) and PASI scores were available were included in the study. IAB was defined as if P wave duration was equal to or longer than 120 msec with (advanced IAB) or without (partial IAB) biphasic P morphology in the inferior electrocardiographic leads. The prevalence of IAB in patients with psoriasis and its relationship with the severity of psoriasis were evaluated in the present study. Results: The mean age was 35 (18-62) years, 53% of the study population were male. The median PASI score was 6. IAB was observed in 9.9% of patients. Partial IAB was observed in 6% of patients whereas the prevalence of advanced IAB was 3.0%. No statistically significant difference was observed between the PASI score in patients with and without IAB [6.0 (3.0-13.5) vs. 7.0 (2.5-22.5), respectively, p=0.35]. The mean P wave duration (PWD) was 101 (90-111) ms. No statistically significant correlation was observed between PWD and the PASI score (p=0.35, r=0.06). Conclusion: No significant correlation was identified between IAB and the PASI score, which is used for assessing the severity of psoriasis.

Prevention and risk assessment of cardiovascular events in a population of patients with psoriasis and psoriatic arthritis

“…The risk of arrhythmia is additionally increased by factors predisposing to cardiovascular incidents accompanying severe Ps [37]. The process inducing this phenomenon is inflammation, which contributes to the oxidative damage in the left atrial tissue, thereby impairing its function [38]. The reduction of blood flow velocity in the left atrium (usually caused by the extension of inflammation to the atrium and/or atrial fibrosis) results in thrombus formation, which may eventually lead to an ischemic stroke.…”