The relationship between maternal age, body mass index and the rate of preterm birth

Abstract

Objective:The aim of the present study was to assess the influence of maternal age and maternal body mass index of early pregnancy on the risk of preterm delivery.Material and Methods:The study included 2.1 million liveborn single newborns with documented data at perinatal surveys. Statistical analyses were performed using the SPSS statistics program.Results:The risk of preterm births increased in obese women and in women with advanced age.Conclusion:Strategies should be developed to reduce preconceptional body mass index, and guidelines are required to help advise women who postponed childbearing.

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“…A retrospective study conducted by Dudenhausen JW et al Found that the incidence of preterm labor increased significantly in multiparous women and gestational age more than 30 weeks. 16 However in this study, preterm labor was most common in nullipara group of the two intervention groups. The incidence of threatened preterm labor is most common in 33-34 weeks for the Nifedipine group and 32-33 weeks for the Isoxsuprine group.…”

Comparison of Nifedipine and Isoxsuprine to Cervical Length in Threatened Preterm Labor

“…Maternal age, occupation, education, gravid status, gestational age could influence the incidence of prematurity. 16 Maternal age is an important factor in threatened preterm labor. According to Astolfi et al described that maternal age >40 years is closely related to incidence of preterm labor.…”

Obesity in pregnant women: a 20-year analysis of the German experience

“…Maternal obesity is one of the most common risk factors for pregnancy complications (multivariate analysis): OR 1.77 (95% CI 1.28–2.45); p value = 0.001 [ 2 ] Periconceptional overweight/obesity are linked to a rise in complications during pregnancy such as gestational diabetes mellitus (GDM)/diabetes mellitus (OR 11.0), hypertension/preeclampsia (OR 3.6/OR 4.4), preterm birth <28 + 0 weeks (OR 2.9) [ 3 , 4 ], but also an increase of perinatal risks (induced labor, postterm birth, vaginal-operative delivery, cesarean section [obesity III°: 47.4% vs. normal weight: 26.5%], anesthetic complications, wound infection and venous thromboembolism) [ 2 , 5 – 9 ]. As far as the fetus is concerned, the following complications can be observed: fetal macrosomia (≥4.000 g) OR 1.97, 95% CI 1.88–2.06 [ 10 , 11 ]; high birth weight (LGA—large for gestational age) OR 2.08, 95% CI 1.97–2.17) [ 12 ]; perinatal complications (cephalopelvic disproportion, hypoxia/asphyxia, shoulder dystocia, impacted fetus at cesarean section, neonatal injury and neonatal/postneonatal death) [ 7 , 13 – 17 ].…”