The Relationship of Dehydration and Overhydration of the Blood Plasma to Collapse in the Management of Artificial Fever Therapy 1

Brown, Herbert R.; Clark, William F.; Jones, Nathaniel S.; Walther, Johanna; Warren, Stafford L.

doi:10.1172/jci101417

Cited by 12 publications

(1 citation statement)

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“…Overhydration can lead to tachypnea, edema, cardiac failure, and death. 7 Because of the the risk of overhydration, the World Health Organization recommends that children who are severely dehydrated are given rapid IV therapy only with close monitoring. 8 However, children who receive a bolus have a 3.3% point greater risk of death than those who do not receive a bolus.…”

Section: Introductionmentioning

confidence: 99%

Maji: A New Tool to Prevent Overhydration of Children Receiving Intravenous Fluid Therapy in Low-Resource Settings

Shah

Skerrett

Nojoomi

et al. 2015

The American Society of Tropical Medicine and Hygiene

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Abstract. We designed and evaluated the accuracy and usability of a device to regulate the volume of fluid dispensed during intravenous drip therapy. The mechanical system was developed in response to a pressing need articulated by clinicians in pediatric wards throughout sub-Saharan Africa, who require a tool to prevent overhydration in children receiving intravenous fluid in settings that lack burettes or electronic infusion pumps. The device is compatible with most intravenous bags and limits the volume dispensed to a preset amount that can be adjusted in 50 mL increments. Laboratory accuracy over a range of clinically-relevant flow rates, initial bag volumes, and target volumes was within 12.0 mL of the target volume. The ease of use is "excellent," with a mean system usability score of 84.4 out of 100. Use of the device limits the volume of fluid dispensed during intravenous therapy and could potentially reduce the morbidity and mortality associated with overhydration in children receiving intravenous therapy.

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Section: Introductionmentioning

confidence: 99%