The Relationship of Nerve Conduction Velocity (NCV) Amplitude with Controlled and Uncontrolled Diabetes Mellitus based on HBA1C in Peripherals Polyneuropathy Patients in Sanglah Hospital

Abstract

Background: Complications microangiopathy in the field of nerves resulting from diabetes mellitus is diabetic neuropathy. Patients with diabetes mellitus with blood glucose levels that are not regulated well have a 25.6% risk of developing neuropathy. Neuropathy can be diagnosed clinically, the presence of complaints such as numbness, tingling, or burning in the distal extremity, but almost half of patients are asymptomatic, other methods to determine the presence of neuropathy are questionnaires and electrodiagnostic examinations which are the gold standard. The purpose of this study was to find the relationship between the amplitude of nerve conduction velocity (NCV) with controlled and uncontrolled diabetes mellitus based on HBA1c in patients with peripheral diabetic polyneuropathy at Sanglah Hospital. Method: This study was conducted with a case-control analytic design at Sanglah Hospital by taking data retrospectively where patient data were directly taken from January 2021-October 31 2021 Results: There were 40 research subjects where 20 subjects with controlled DM and 20 subjects with uncontrolled DM, 62.5% men, with an age range of 50-60 years, BMI obesity, duration of diagnosis > 3 years where the results obtained were peripheral polyneuropathy conditions. with the results of NCV only found a significant difference in CMAP N Median with p 0.026 and in SNAP with p = 0.035 in SNAP Conclusion: All patients have the result of decreased function of NCV with the highest risk if it is not controlled with HBA1C levels < 7%, there will be the greatest decrease in NCV motor and sensory N. radialis. Keywords: diabetes mellitus, CMAP, HBA1C, NCV, SNAP.