The Relative Biological Effectiveness of Fast-Neutron and X-Radiation

Dose-Dependence of Fast Neutron RBE for Lens Opacification in Mice

“…It utilizes 15 progressively larger divisions instead of the three or four arithmetically progressive divisions conventionally used to cover the ränge from 0 to 100 % opacity (6,9,10). The small intervals toward the lower end of this visual scale appear justified on the basis of sensitivity and reproducibility tests.…”

Scanning Electron Microscopy of X-Ray-Induced Cataract in Mice on Normal and Galactose Diet

“…The development of X-ray cataract in mice has been carefully followed in previous studies [Upton et al, 1953;Riley et al, 1956], Cataracts have been induced in these animals with as low as 16 R after a long latent period of nearly 3 years [Upton et al, 1953], The choice of X-ray dosage in our experiments (1,000 rad) was chosen to shor ten the latent period. With this level of exposure to X-ray, mature cataracts developed in 4 months.…”

Comparison of the Biological Efficiency of Fast Neutrons and Caesium Gamma-rays on ‘August’ Rats

“…of neutrons also varies considerably if it is determined by the late effects. The figures obtained range from 2.5 to 5.0 for the production of lens opacities (Riley, Evans, Rhody, Leinfelder andRichards 1956, Upton, Christenberg, Melville, Furth andHurst 1956); from 2 to 3 for the production of gastro-intestinal tumours (Nowell and Cole 1959); and of the order of 2.2 for the reduction of life-span in mice (Curtis and Gebhard 1958). Spalding, Hawkins and Strang (1958) studied the reduction of fertility on CFL male mice and found the R.B.E.…”