The Relative Changes in Afferent and Efferent Arteriolar Resistance in the Normal Human Kidney

Improvements in Calculation of Renal Resistance to Blood Flow. Charts for Osmotic Pressure and Viscosity of Blood

“…Our study indicated that, in this physiological range, both sets of arterioles, rather than only one, participated (11).…”

“…That is to say, as blood flow increases, glomerular intra-capillary pressure falls until, if carried to a theoretical (not physiological) extreme, it will be the same as peritubular capillary pressure and will be inadequate to form a glomerular filtrate. This is the meaning of the extreme foot of the curve previously reported (11). It is not meant to be a physiological occurrence, since our formulas were carefully limited to physiological ranges so as to prevent drawing such impractical conclusions.…”

“…In this way, values for "hydraulic" resistance of the renal arterioles and the rest of renal resistance can be obtained, which give a notion of the calibre of these vessels, irrespective of the viscosity cf the blood coursing through them. (9,11,12).…”

Studies in Renal Circulation During Periods of Life Stress and Accompanying Emotional Reactions in Subjects With and Without Essential Hypertension; Observations on the Role of Neural Activity in Regulation of Renal Blood Flow 1

“…This was considered as evidence that, in the absence of the renal nerve supply so far as could be determined, the kidney nevertheless continued to control its blood flow. In an attempt to determine more fully where the site of this resistance was located, the data available from all the subjects, with and without sympathectomy were re-evaluated by means of the formulae of Lamport (16,(20)(21)(22) for the calculation of efferent and afferent arteriolar resistance. The results of these calculations (Table III) indicated that there was a rise in both afferent and efferent arteriolar resistance in all 35 subjects without sympathectomy.…”

Formulae for Afferent and Efferent Arteriolar Resistance in the Human Kidney: An Application to the Effects of Spinal Anesthesia

“…They find that the perfusion pressure plotted against the flow is a straight line with an intercept at about 20 mm. of 6 The cortical tissues are mainly nourished by glomerular filtrate on its way to the capillaries. mercury.…”