A factorial field experiment on wheat crop was conducted during two successive growth seasons of (2009/2010) ; (2010/2011) as two different On-farm trials sited in El-Dakahlia Governorate. The factors involved organic manuring from two biological treating composts of rates (0, 10 and 20 m 3 .fed-1) and NPKZn-mineral fertilization of the optimum recommended rates. The two experimental sites were clayey in texture have the average values of salinity index ECe = 3.8 dS.m-1 ; pH = 7.8 and the available soil forms of N , P , K and Zn nutrients were : 30 , 19 , 600 , 0.6 ; respectively. The obtained results indicated the following points : 1-Such soils have to be manured with composts and fertilized with optimum recommended NPKZn-mineral fertilizers for obtaining higher wheat yields. 2-Grain and straw yields have been increased significantly as a result of adding organic manuring (in forms of composts). Higher wheat yields were realized by applying (10 or 20 m 3 .fed-1) treatments. 3-The biological treated compost realized economically higher values of wheat yield relative to the untreated one. 4-The NPKZn-mineral fertilization with optimum recommended rates has increased the values of such wheat parameters. 5-The significant interaction effects of organic composting and NPKZn-mineral cofertilization indicated that : the highest yield and its component were obtained by applying the treatment of (bio-treating compost of 10m 3 .fed.-1). Along with optimum recommended rates of NPKZn mineral fertilizers.