The Residues of Antibiotics (Tetracycline, Oxolinic Acid and Ciplofloxacin) and Malachite Green in Cultured Rainbow Trout

Kim, Young‐Mog; Lee, Myung-Suk; Chung, Yong-Ho

doi:10.13000/jfmse.2013.25.4.828

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…In addition, the risk of contamination of products by chemical agents is greater in freshwater than in seawater (28,29). Chemical agents such as malachite green and crystal violet are not approved worldwide as veterinary drugs for fish because of their carcinogenicity and mutagenicity (30), but such agents are used illegally due to their low cost and high efficiency (31).…”

Section: Resultsmentioning

confidence: 99%

“…Accordingly, consumers are reluctant to consume aquaculture products that might have been exposed to hazardous chemicals or antibiotics. However, few studies have examined the levels of banned chemical and residual antibiotic in freshwater aquaculture fish (11,29). Therefore, we evaluated the levels of banned chemicals and residual antibiotics in seven freshwater aquaculture species.…”

Section: Resultsmentioning

confidence: 99%

“…Kim et al (29) investigated the levels of residues of malachite green and antibiotics (tetracycline, oxolinic acid, and ciprofloxacin) in cultured rainbow trout (Oncorhynchus mykiss) collected in 22 aquaculture farms (2 in Gyeonggi-do, 12 in Gangwon-do, and 8 in Gyeongsangbuk-do) in January and July 2008 and January and August 2009. Malachite green was not detected in any samples tested in the study.…”

Section: Resultsmentioning

confidence: 99%

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Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species

Choi

Park

Kim

et al. 2016

Food Sci Biotechnol

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This survey was performed to estimate the levels of pathogenic microorganisms, antibiotic residues, and heavy metals in seven Korean freshwater aquaculture species including ,, ,, ,, and . None of the ten foodborne pathogens tested in this study were found in any of the species collected from any of the aquaculture farms. Furthermore, no banned chemicals or antibiotic residues were found in any of the species collected from any of the aquaculture farms, except enrofloxacin, which was below guideline limits (0.1 mg/kg). Finally, no species had lead, cadmium, total arsenic, or total mercury concentrations above the Ministry of Food and Drug Safety (MSDF) guidelines (0.5, 0.5, 0.1, and 0.5 mg/kg, respectively). These results ensure the safety of freshwater aquaculture species and will be useful for developing consumption advisories of freshwater fishes.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species

Choi

Park

Kim

et al. 2016

Food Sci Biotechnol

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“…They reported that these levels were below the MRL laid down in Korean Food Legislation. Furthermore Kim et al (2013) analyzed the presence of tetracycline residues in a study in trout in the Republic of Korea. Tetracycline residue was below 200 µg/kg and it was found that this level was below the MRL laid down in Korean legislation.…”

Section: Discussionmentioning

confidence: 99%

Investigation of tetracycline residues in fish caught from surrounding fish farms in Mugla district

Türk¹,

Oguz²

2016

EurasianJVetSci

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ÖzAmaç: Su ürünlerindeki ilaç ve metabolitlerinin kalıntı analizleri Ulusal Kalıntı İzleme Planı kapsamında düzenli olarak yapılmaktadır. Fakat Türkiye'de bu kalıntıların sucul ortama etkilerine yönelik araştırmalar sınırlıdır. Bu çalışmada, Muğla bölgesindeki balık çiftliklerinin etrafından avlanan balıklarda tetrasiklin grubu antibiyotiklerin (oksitetrasiklin, tetrasiklin, klortetrasiklin, doksisiklin) kalıntılarının belirlenmesi amaçlandı. Gereç ve Yöntem:Analiz için 70 ayrı çiftlik etrafından toplanan 70 adet balık örneği kullanıldı. Balıklarda tetrasiklin kalıntıları LC MS/MS yöntemi ile analiz edildi. Seçicilik, doğ-rusallık, geri kazanım, duyarlılık ve kesinlik ölçütlerinde metot validasyonu yapıldı. Bulgular:Analizin geri kazanımları oksitetrasiklin için %100.5, tetrasiklin için %101.3, klortetrasiklin için %99 ve doksisilin için %100.5 olarak belirlendi. Analizlerin sonucunda balık örneklerinin hiçbirinde tetrasiklin grubu antibiyotikler tespit edilemedi.Öneri: Yapılan analizlerde balık örneklerinde hesaplanabilir limitlerde tetrasiklin kalıntısı bulunmaması çevre ve halk sağlığı açısından memnuniyet verici olarak kabul edilebilir. Anahtar kelimeler: Balık, tetrasiklin, kalıntı, LC MS/MS AbstractAim: Residue analyses of drugs and metabolites in the aquaculture are regularly conducted under the National Residue Monitoring Plan in Turkey. However, the research on the impact of these residues on the aquatic environment is limited. In this study, it was aimed to analyze the residues of tetracycline group antibiotics in fishes caught around fish farms in the Muğla district. Materials and Methods:Seventy fish samples collected from the vicinity of 70 different fish farms were used for analysis. Tetracycline residues in the fish were analyzed with the LC MS/MS method. Validation was performed with the criteria of specificity, linearity, recovery, precision and sensitivity.Results: Recovery values were determined as follows: Oxytetracycline 100.5%, tetracycline 101.3%, chlortetracycline 99%, and doxycycline 100.5%. At the end of the analyses, no tetracycline antibiotic residues were found. Conclusion:It can be expressed that no tetracycline residues were detected in the samples at the detectable limits is a satisfactory result in terms of public health and environment.

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Monitoring of Malachite Green in Freshwater Fish using LC-MS/MS

Choi¹,

Yuk²,

Park³

et al. 2016

J. Fd Hyg. Safety

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The Residues of Antibiotics (Tetracycline, Oxolinic Acid and Ciplofloxacin) and Malachite Green in Cultured Rainbow Trout

Cited by 4 publications

References 8 publications

Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species

Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species

Investigation of tetracycline residues in fish caught from surrounding fish farms in Mugla district

Monitoring of Malachite Green in Freshwater Fish using LC-MS/MS

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