The revolution of cosmeceuticals delivery by using nanotechnology: A narrative review of advantages and side effects

Hajleh, Maha N. Abu; Abu‐Huwaij, Rana; Al‐Samydai, Ali; Al-Halaseh, Lidia; Al-Dujaili, Emad A S

doi:10.1111/jocd.14441

Cited by 38 publications

(19 citation statements)

References 77 publications

(215 reference statements)

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“…NEs can be formulated as creams, lotions, shampoos, foams, sprays, and aerosols. They are major carriers for antiwrinkle formulations, sunscreens, and cleansing solutions 73 …”

Section: Pharmaceutical Applications Of Nes For Cosmeceutical Deliverymentioning

confidence: 99%

Recent exploration of nanoemulsions for drugs and cosmeceuticals delivery

Abu‐Huwaij

Al‐Assaf

Hamed

2021

J of Cosmetic Dermatology

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Background: Nanoemulsions (NEs) have been explored as nanocarriers for the delivery of many drugs and cosmeceuticals. The extraordinary expansion of using NEs is due to their capability to conquer the main challenges of conventional delivery systems such as short residence time with low patient acceptance, poor stability, low aqueous solubility, permeability, and hence bioavailability. Methods:This review recapitulated the most recent pharmaceutical and cosmeceutical applications of NEs as effective delivery nanocarriers. The outputs of our research studies and the literature review on the latest NEs applications were assessed to highlight the NEs components, preparations, applications, and the improved quality and elegance of the used product.Results: NEs are stable submicronic translucent dispersions with narrow droplet size distribution. They exhibited excellent ability to efficiently encapsulate therapeutics of diverse nature of drugs and cosmeceuticals. NE formulations showed superiority over conventional delivery approaches with overabundances of advantages through different routes of administration. This novel technology exhibited better aesthetic appeal, higher bioavailability, and a longer duration compared to the conventional delivery systems. Conclusion:This novel technology holds promise for different therapeutics fields.However, the success of NEs use advocated the development of robust formulations, proper choice of equipment, ample process characterization, and assurance of their efficacy, stability, safety and cosmetic appeal.

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“…NEs can be formulated as creams, lotions, shampoos, foams, sprays, and aerosols. They are major carriers for antiwrinkle formulations, sunscreens, and cleansing solutions 73 …”

Section: Pharmaceutical Applications Of Nes For Cosmeceutical Deliverymentioning

confidence: 99%

Recent exploration of nanoemulsions for drugs and cosmeceuticals delivery

Abu‐Huwaij

Al‐Assaf

Hamed

2021

J of Cosmetic Dermatology

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“…The properties of EGCG, like the various flavonoids mentioned in this work, have properties that attend to some of the molecular, biochemical, and cellular disorders caused by photoaging. Which is very interesting since several of the treatments developed with the damage generated by UV radiation have a cosmetic approach instead of a therapeutic one; that is, they are designed to reduce wrinkles and spots on the skin, leaving aside the severe damage at cellular level caused by radiation and ROS, which can cause other diseases, such as skin cancer [ 92 , 93 , 94 , 95 ]. Therefore, flavonoids could be proposed in the design of new cosmeceutical products, which have a cosmetic approach as well as a therapeutic one; that is, they attend to health and beauty.…”

Section: Anti-photoaging and Photoprotective Properties Of Flavonoidsmentioning

confidence: 99%

Flavonoids Present in Propolis in the Battle against Photoaging and Psoriasis

Rivera-Yañez

Ruiz-Hurtado²,

Mendoza-Ramos

et al. 2021

Antioxidants

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The skin is the main external organ. It protects against different types of potentially harmful agents, such as pathogens, or physical factors, such as radiation. Skin disorders are very diverse, and some of them lack adequate and accessible treatment. The photoaging of the skin is a problem of great relevance since it is related to the development of cancer, while psoriasis is a chronic inflammatory disease that causes scaly skin lesions and deterioration of the lifestyle of people affected. These diseases affect the patient’s health and quality of life, so alternatives have been sought that improve the treatment for these diseases. This review focuses on describing the properties and benefits of flavonoids from propolis against these diseases. The information collected shows that the antioxidant and anti-inflammatory properties of flavonoids play a crucial role in the control and regulation of the cellular and biochemical alterations caused by these diseases; moreover, flavones, flavonols, flavanones, flavan-3-ols, and isoflavones contained in different worldwide propolis samples are the types of flavonoids usually evaluated in both diseases. Therefore, the research carried out in the area of dermatology with bioactive compounds of different origins is of great relevance to developing preventive and therapeutic approaches.

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“…These compounds are known together as biogenic nanoparticles. Here, we present an update on recent breakthroughs in the synthesis of biological nanoparticles and outline their future development and potential uses ( Abu Hajleh et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Green Metallic Nanoparticles: Biosynthesis to Applications

Chopra

Bibi

Singh

et al. 2022

Front. Bioeng. Biotechnol.

130

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Current advancements in nanotechnology and nanoscience have resulted in new nanomaterials, which may pose health and environmental risks. Furthermore, several researchers are working to optimize ecologically friendly procedures for creating metal and metal oxide nanoparticles. The primary goal is to decrease the adverse effects of synthetic processes, their accompanying chemicals, and the resulting complexes. Utilizing various biomaterials for nanoparticle preparation is a beneficial approach in green nanotechnology. Furthermore, using the biological qualities of nature through a variety of activities is an excellent way to achieve this goal. Algae, plants, bacteria, and fungus have been employed to make energy-efficient, low-cost, and nontoxic metallic nanoparticles in the last few decades. Despite the environmental advantages of using green chemistry-based biological synthesis over traditional methods as discussed in this article, there are some unresolved issues such as particle size and shape consistency, reproducibility of the synthesis process, and understanding of the mechanisms involved in producing metallic nanoparticles via biological entities. Consequently, there is a need for further research to analyze and comprehend the real biological synthesis-dependent processes. This is currently an untapped hot research topic that required more investment to properly leverage the green manufacturing of metallic nanoparticles through living entities. The review covers such green methods of synthesizing nanoparticles and their utilization in the scientific world.

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The revolution of cosmeceuticals delivery by using nanotechnology: A narrative review of advantages and side effects

Cited by 38 publications

References 77 publications

Recent exploration of nanoemulsions for drugs and cosmeceuticals delivery

Recent exploration of nanoemulsions for drugs and cosmeceuticals delivery

Flavonoids Present in Propolis in the Battle against Photoaging and Psoriasis

Green Metallic Nanoparticles: Biosynthesis to Applications

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