2011
DOI: 10.1016/j.tim.2010.12.008
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The rise and fall of the Mycobacterium tuberculosis genome

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Cited by 66 publications
(71 citation statements)
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“…M. kansasii is the environmental organism that phenotypically resembles M. tuberculosis most closely and this relationship has been supported by genomic comparisons [79][80][81]. Cogent arguments have been advanced to associate the evolution of ancient tubercle bacilli, such as "M. canettii", with bacteria similar to M. kansasii, including indications of horizontal gene transfer between these taxa [80,81]. Key genes acquired by horizontal gene transfer include those coding for mycobacterial lipids, transferases and proteins related to adaptation to anaerobic conditions [80,81].…”
Section: Evolutionary and Pathogenicity Aspects Of Cell Envelope Compmentioning
confidence: 84%
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“…M. kansasii is the environmental organism that phenotypically resembles M. tuberculosis most closely and this relationship has been supported by genomic comparisons [79][80][81]. Cogent arguments have been advanced to associate the evolution of ancient tubercle bacilli, such as "M. canettii", with bacteria similar to M. kansasii, including indications of horizontal gene transfer between these taxa [80,81]. Key genes acquired by horizontal gene transfer include those coding for mycobacterial lipids, transferases and proteins related to adaptation to anaerobic conditions [80,81].…”
Section: Evolutionary and Pathogenicity Aspects Of Cell Envelope Compmentioning
confidence: 84%
“…A consensus is developing that an attractive evolutionary pathway can be envisaged from environmental Mycobacterium kansasii, through "M. canettii" to all the modern biotypes of the M. tuberculosis complex [79][80][81][82][83]. M. kansasii is the environmental organism that phenotypically resembles M. tuberculosis most closely and this relationship has been supported by genomic comparisons [79][80][81]. Cogent arguments have been advanced to associate the evolution of ancient tubercle bacilli, such as "M. canettii", with bacteria similar to M. kansasii, including indications of horizontal gene transfer between these taxa [80,81].…”
Section: Evolutionary and Pathogenicity Aspects Of Cell Envelope Compmentioning
confidence: 99%
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“…Another specific adaptation is anaerobic respiration. 37,38 Ancestral genetic events could explain the sequential evolution of the pathogen and the ongoing functional characterization of these events could be reconstructed in M. kansasii or M. marinum.…”
Section: Mycobacterium Tuberculosis: a Closer Lookmentioning
confidence: 99%