The role of 24 h pH-recording in pediatric otolaryngologic gastro-esophageal reflux disease

Abbeele, Thierry Van Den; Couloigner, V.; Fauré, Christophe; Narcy, P

doi:10.1016/j.ijporl.2003.08.038

Cited by 34 publications

(7 citation statements)

References 15 publications

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“…The present study used the dual-probe 24-h pH-monitoring that is considered to be the ''gold standard'' examination for diagnosis of gastroesophageal reflux [5,[28][29][30][31]. Although, other tests exist and have been widely used to assess gastroeophageal reflux (barium esophagography, radionuclide scintigraphy, lipid-laden macrophage sampling, modified Bernstein testing, oesophageal manometry, and endoscopy with or without biopsy) and at some time have been held to be the standard for documenting GERD, they have a major shortcoming: their relatively poor sensitivity and/or specificity [5,[32][33][34][35].…”

Section: Case Sexmentioning

confidence: 99%

Recurrent acute otitis media and gastroesophageal reflux disease in children. Is there an association?

Kotsis

Nikolopoulos

Yiotakis

et al. 2009

International Journal of Pediatric Otorhinolaryngology

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Section: Case Sexmentioning

confidence: 99%

Recurrent acute otitis media and gastroesophageal reflux disease in children. Is there an association?

Kotsis

Nikolopoulos

Yiotakis

et al. 2009

International Journal of Pediatric Otorhinolaryngology

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“…The existence of proton pump activity with a functional role in normal and/or pathological laryngeal tissue has been recently suggested. 28 More research is still needed for a conclusion about these processes. Is it possible that some patients with respiratory symptoms produce "acids" in the larynx, when adequately stimulated, resulting in reflux?…”

Section: Resultsmentioning

confidence: 99%

pH nasofaríngeo e refluxo gastroesofágico em crianças com doença respiratória crônica

Junqueira

Penna²

2007

J. Pediatr. (Rio J.)

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Objectives: The aim of this case-control study was to evaluate the nasopharyngeal pH (NasopH) in children with normal or abnormal pH-metry in two groups of patients: 1) children presenting gastroenterological symptoms; and 2) children with chronic respiratory symptoms. Methods:From February 2004 to January 2005, all consecutive patients referred for 24-hour pH-metry and in whom gastroesophageal reflux disease was suspected were enrolled in a prospective study. They were assigned to four groups: gastroenterological symptoms with normal (A) or abnormal (B) pH-metries (GG), and chronic respiratory symptoms with normal (C) or abnormal (D) pH-metries (RG). NasopH was measured for 5 minutes, before the 24-hour test was performed.Results: Thirty-eight pH-metry tests were included (20 in the RG and 18 in the GG). Abnormal pH-metry results were observed in 11 patients in the GG and in 12 in the RG. NasopH means were 6.3273 and 5.6917, respectively (p < 0.0001). Average nasopharyngeal pH was 5.6917 among the 12 RG patients with abnormal pH-metry results and 6.5000 among the remaining eight patients with normal test results (p = 0.0006). Analysis of the RG with a receiver operating characteristic (ROC) curve showed pH of 5.8 as cutoff point (sensitivity of 91.7% and specificity of 87.5%).The area below the ROC curve was 0.870. Conclusions:Nasopharyngeal pH is significantly lower among patients in the RG presenting abnormal pH-metry results. A 5.8 NasopH has good sensitivity and specificity and can be used as a screening test in patients with chronic respiratory diseases to select those for whom conventional 24-hour pH-metry is indicated.J Pediatr (Rio J). 2007;83(3):225-232: Gastroesophageal reflux/complications/diagnosis, child, evaluation studies, nasopharynx, esophageal pH monitoring.

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“…The same result was reported by several studies that determined that the prevalence of GERD in children with OME ranged from 55.6 to 64%. 20,21 On the other hand, Abd El-Fattah et al 22 found that the percentage of GERD in OME was 17.6%. The different result could be explained by different methodology in the study conducted by Abd El-Fattah et al 22 In that study, the children complaining of OME were submitted to ventilation tube, tonsillectomy and adenoidectomy, and then assessed pH after recovery from surgery.…”

Section: Discussionmentioning

confidence: 99%

Outcome of Gastroesophageal Reflux Therapy in Children with Persistent Otitis Media with Effusion

Elbeltagy

Abdelhafeez

2021

Int Arch Otorhinolaryngol

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Introduction Otitis media with effusion (OME) is considered one of the most common disorders that affect children during the first years of life. There are many risk factors of persistent middle ear effusion; one of these risk factors is gastroesophageal reflux. Association between persistent OME and gastroesophageal reflux diseases (GERDs) could be explained by respiratory tract infections, insufficient ciliary clearance, and poor drainage of the Eustachian tube. Objective To investigate whether the control of gastroesophageal reflux plays a role in the management of persistent OME and decreases tympanostomy tube insertion Method A cross-sectional study was conducted on 50 children complaining of persistent OME. Their ages ranged between 5 and 12 years old. All children were subjected to full history taking, audiological assessment and 24-hour esophageal pH monitoring. The study group was divided according to pH results into two groups: GERD positives and GERD negatives. Result The prevalence of GERD in persistent OME was 58%. There were statistically significant differences in the hearing levels and middle ear condition before and after the treatment (p < 0.05). The percentage of improvement of children complaining of persistent OME after antireflux treatment was 52%. Conclusion Gastroesophageal reflux disease should be considered in patients with persistent OME. The administration of proton pump inhibitor (PPI) can set aside superfluous surgical treatment (such as tympanostomy).

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The role of 24 h pH-recording in pediatric otolaryngologic gastro-esophageal reflux disease

Cited by 34 publications

References 15 publications

Recurrent acute otitis media and gastroesophageal reflux disease in children. Is there an association?

Recurrent acute otitis media and gastroesophageal reflux disease in children. Is there an association?

pH nasofaríngeo e refluxo gastroesofágico em crianças com doença respiratória crônica

Outcome of Gastroesophageal Reflux Therapy in Children with Persistent Otitis Media with Effusion

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