The role of echocardiography in guiding management in dilated cardiomyopathy

Thomas, Deepak; Wheeler, Richard; Yousef, Zaheer; Masani, Navroz

doi:10.1093/ejechocard/jep158

Cited by 58 publications

(43 citation statements)

References 35 publications

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“…In one study, tricuspid diastolic velocity by tissue Doppler was found to be a good prognostic measure, especially in children 13 . Other markers include LV sphericity index, diastolic filling period, presence of valvular regurgitation and presence of right ventricular changes 3 . However, these measurements need specialized machines and more importantly, trained technicians, which is not always available.…”

Section: Discussionmentioning

confidence: 99%

“…Besides the basic pulse-Doppler echocardiography, many new techniques are now being used for better evaluation of cardiac structure and function in DCM, like tissue Doppler and speckle tracking. Echocardiography is important not only for diagnosis of the condition but also to assess prognosis and guide therapeutic interventions 3 . Besides ejection fraction, other echocardiographic measures like left and right ventricular dimensions and left atrial size and volume are also important for prognosis in these patients 3 .…”

Section: Introductionmentioning

confidence: 99%

“…Echocardiography is important not only for diagnosis of the condition but also to assess prognosis and guide therapeutic interventions 3 . Besides ejection fraction, other echocardiographic measures like left and right ventricular dimensions and left atrial size and volume are also important for prognosis in these patients 3 . Of these different dimensions left atrial size (LAS) is now considered as an important marker of cardiac function 4 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Echocardiographic study on Dilated Cardiomyopathy from Eastern India

Paul¹,

Nandi²,

Sinha³

2014

Int Jour of Biomed Res

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Echocardiographic study on Dilated Cardiomyopathy from Eastern India

Paul¹,

Nandi²,

Sinha³

2014

Int Jour of Biomed Res

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“…беременности или в течение 5 мес. после родов, от имеющей худший про-гноз дилатационной кардиомиопатии (ДКМП) [1][2][3].…”

Section: Modern Methods Of Intracardiac Hemodynamics and Cardiac Defounclassified

Modern Methods of Intracardiac Hemodynamics and Cardiac Deformability Assessment in Pregnant Women With Dilation Cardiomyopathy Syndrome

Дорошенко¹,

Zubarev²,

Lapochkina³

et al. 2016

Russ J Cardiol

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Цель. Поиск возможных дополнительных дифференциально-диагностических критериев у пациенток с синдромом дилатационной кардиомиопатии (СДКМП) на основе оценки результатов деформации миокарда (ДМ) в режиме монито-ринга. Материал и методы. Обследовано 28 беременных с СДКМП, из них 10 -в возрасте 29±5,8 лет с постмиокардитическим кардиосклерозом и СДКМП, и 18 -без указаний на перенесенный миокардит и СДКМП в анамнезе. Группу конт роля составили 30 беременных пациенток с нормальной систолической и насосной функцией сердца и не измененной геометрией левого желудочка (ЛЖ). Всем пациенткам проводился суточный мониторинг ЭКГ и артериаль-ного давления. УЗИ сердца выполнялись по общепринятому протоколу в B-режиме, режимах импульсного и постоянного допплера, цветового доп-плеровского картирования с оценкой размеров полостей, внутрисердечной гемодинамики, давления в стволе легочной артерии и продольной, радиаль-ной, циркулярной глобальной систолической ДМ и скорости смещения соот-ветствующих волокон миокарда ЛЖ. Результаты. У беременных 1-й и 2-й гр. отмечены достоверные нарушения показателей силы и скорости миокарда наряду с негативным ремоделирова-нием полости ЛЖ по сравнению с гр. контроля. При сравнении между собой показателей 1-й и 2-й гр. было выявлено достоверное снижение продольной и циркулярной глобальной систолической ДМ у пациенток 1 гр. Заключение. Кроме оценки анатомии, внутрисердечной гемодинамики, систолической и насосной функции сердца у беременных с СДКМП целесо-образно использовать дополнительные диагностические критерии в виде показателей продольной, радиальной, циркулярной глобальной систоличе-ской ДМ. Aim. The search for plausible additional criteria of diagnosis in patients with the syndrome of dilation cardiomyopathy (SDCMP) on the basement of deformity of myocardium (MD) assessment results in life mode. Material and methods. Totally, 28 pregnant with SDCMP studied, of those 10 at the age 29±5,8 y. with postmyocarditis cardiosclerosis and SDCMP, and 18 -without anamnestic data of myocarditis or SDCMP. Controls consisted of 30 pregnant women with normal systolic and pumping heart function, and non-changed geometry of the left ventricle (LV). All patients underwent 24-hour ECG and blood pressure monitoring. USE of the heart was done by the common protocol in B-regimen, impulse and continuous Doppler, color Doppler with chambers size measurement, intracardiac hemodynamics, pressure in pulmonary artery stem, and longitudinal, radial and circular global systolic MD and velocity of the shift of respective LV myocardial fibers.Results. In the pregnant of 1st and 2nd groups there were significant disorders of the force and velocity of myocardium, together with negative remodeling of LV chamber, comparing to the controls. While comparing the parameters of 1 and 2 groups, there was significant decrease of longitudinal and circular global systolic MD in patients of the 1 group. Conclusion. Except the assessment of anatomy, intracardiac hemodynamics, systolic and pumping function of the heart of the pregnant with ...

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“…Right Ventricular (RV) functions are known to have a prognostic impact on Non-Ischemic Dilated Cardiomyopathy (NICMP), similar to all forms of heart failure (1,2). RV failure due to primary Left Ventricular (LV) systolic dysfunction has been proven to be associated with worsening symptoms, hemodynamic and clinic deterioration, and increased mortality in various studies (1)(2)(3).…”

Section: Introductionmentioning

confidence: 99%

Predictors of Right Ventricular Systolic Dysfunction in Non-Ischemic Dilated Cardiomyopathy: An Echocardiographic Study

Karaca¹,

Avcı²,

Babur³

et al. 2016

Int Cardiovasc Res J

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A B S T R A C TBackground: Right Ventricular (RV) functions are known to have an impact on determining the prognosis of patients with Non-Ischemic Dilated Cardiomyopathy (NICMP). Objectives: This study aimed to investigate the echocardiographic determinants of RV systolic dysfunction in patients with NICMP. Patients and Methods: This cross-sectional study was conducted on 79 patients with angiographically normal coronary arteries (mean age: 50.5 ± 12, mean Ejection Fraction (EF): 31 ± 4%) selected through purposive sampling The patients were divided into two groups based on their RV systolic function determined by tissue Doppler systolic velocities (RV-Sm): group A (RV-Sm ≥ 10 cm/s, N = 48) and group B (RV-Sm < 10 cm/s, N = 31). The two groups were compared regarding clinical, demographic, and echocardiographic variables using independent t-test and chi-square test. Results: The patients with RV systolic dysfunction were found to have higher Brain Natriuretic Peptide (BNP) values (P = 0.006) and worse functional status (New York Heart Association (NYHA) III-IV, P = 0.04) compared to group A. Besides, univariate analysis of the echocardiographic parameters revealed that the patients in group B had significantly (all P values < 0.05) higher Left Atrial Volume Index (LAVI), higher degree of left ventricular diastolic dysfunction (represented by LV-E/Em), higher degree of Functional Mitral Regurgitation (FMR), higher estimated Pulmonary Artery Systolic Pressure (PASP), and higher degree of RV diastolic dysfunction (represented by RV-E/ Em) Moreover, multivariate logistic regression analysis showed that severe FMR (P = 0.006) and RV-E/Em (P = 0.016) predicted RV systolic dysfunction independently. Conclusions: Advanced FMR and worse RV diastolic functions emerged as the independent predictors of RV systolic dysfunction in NICMP correlating to functional status and BNP levels.

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The role of echocardiography in guiding management in dilated cardiomyopathy

Cited by 58 publications

References 35 publications

Echocardiographic study on Dilated Cardiomyopathy from Eastern India

Echocardiographic study on Dilated Cardiomyopathy from Eastern India

Modern Methods of Intracardiac Hemodynamics and Cardiac Deformability Assessment in Pregnant Women With Dilation Cardiomyopathy Syndrome

Predictors of Right Ventricular Systolic Dysfunction in Non-Ischemic Dilated Cardiomyopathy: An Echocardiographic Study

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