This study investigates the fundamental role of collaboration in promoting a culture of continuous innovation in companies, driving them to become serial innovators, as evidenced by their industrial property registrations. Furthermore, it explores, in an innovative way, how various factors, such as the level of technological advancement in the sector, government support for innovation, investments in research and development, the degree of international involvement, and the level of education of employees, influence the probability of a company achieving the status of serial innovator. Based on data extracted from CIS reports spanning from 2012 to 2018, this research employs Logit models to explore the relationship between these variables. The findings clarify the positive impact of collaboration on a company’s ability to sustain innovation over time, thereby establishing itself as a serial innovator. The promotion of collaborative networks and partnerships with external entities, such as partner companies, research institutions, and government organizations, emerges as a powerful strategy for promoting innovation in organizational contexts. Furthermore, the study reveals the critical roles played by public support for innovation, the educational level of the workforce, and investments in R&D in increasing companies’ innovation capabilities. These factors contribute to increasing a company’s propensity for innovation and increasing its likelihood to become a serial innovator. A qualified and educated workforce is known to have the skills and knowledge required to actively engage in innovative activities, thus positioning companies as serial innovators.