The Role of Hair Restoration Surgery in Primary Cicatricial Alopecia

Dahdah, Maurice J.; Iorizzo, Matilde

doi:10.1159/000448104

Cited by 20 publications

(19 citation statements)

References 14 publications

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“…The fact that surgery might induce a relapse should not defer the patient from pursuing HT in CA and deny them their only chance to correct the alopecic defect. [ 11 ]…”

Section: Discussionmentioning

confidence: 99%

The assessment of hair transplantation outcomes in cicatricial alopecia

et al. 2020

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Background: Cicatricial alopecia (CA) is scarring alopecia due to a diverse group of disorders which destroy the hair follicle, replace it with scar tissue causing permanent hair loss. Spontaneous regrowth of hair in CA is rarely seen and thus it has a negative impact on the self-esteem of the patient. However, hair transplantation (HT) has emerged as an effective modality of treatment to replace lost hair for cosmetic benefit. Materials and Methods: This was a prospective analysis of patients affected with CA, who underwent HT from January 2015 to December 2017. Demography of patients along with the duration of disease, stability, biopsy, technique of HT, number of grafts, and other procedures done were noted on a pro forma and analyzed. A test patch of HT was done in all primary CA to assess stability and few secondary CA to look for graft uptake. The patients were followed up for a year and the outcomes were graded by patient and a single observer on a 10 point scale as poor, satisfactory, good, and very good at 3, 6, and 12 months. Results: A total of 50 patients with CA underwent follicular unit extraction. Majority of them were males(84%) with a male to female ratio of 5.25:1. Secondary CA was seen in majority(90%) of the study group. Moustache (56%) was the most common site affected, followed by scalp (22%), beard(14%) and eyebrow(8%). Around 38%(12 atrophic scars; 7 hypertrophic scars) underwent fractional CO2 laser/Erbium YAG laser with or without intralesional steroid injections in a stepwise manner prior to HT. Excellent-to-very good outcome was seen in 82% while 18% were lost for follow up. Conclusion: Scarring in CA has a significant effect on quality of life of affected patients. HT when done taking into consideration the stability of disease has good-to-excellent outcomes thus leading to a positive impact on the patient's life.

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“…The fact that surgery might induce a relapse should not defer the patient from pursuing HT in CA and deny them their only chance to correct the alopecic defect. [ 11 ]…”

Section: Discussionmentioning

confidence: 99%

The assessment of hair transplantation outcomes in cicatricial alopecia

et al. 2020

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“…If the disease is unstable with plenty of inflammatory infiltrate, the implanted follicular grafts might get destroyed with the same mechanism of the underlying disease pathology. Also, in conditions like lichen plano-pilaris, there are chances of koebnerization if the underlying disease activity still persists[ 15 16 ] FUE in thermal burn scar - Burn injuries; whether thermal or chemical; can lead to complete destruction of hair follicles along with severe scarring of tissue. Dermoscopy and histopathological assessment aids in judging the prognosis of FUE in burn scars.…”

Section: Fue In Scarring Alopeciamentioning

confidence: 99%

Follicular Unit Extraction [FUE] – One Procedure, Many Uses

Kerure

Deshmukh

Agrawal

et al. 2021

Indian Dermatology Online Journal

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Follicular unit extraction [FUE] is a minimally invasive hair restoration surgery popularly known for its utility in androgenetic alopecia (AGA). In FUE, individual follicular grafts are extracted from donor area and implanted in the recipient area. Advantages of FUE are that it is comparatively 'scarless', has faster healing time, has less downtime and requires less technical staff. This article is aimed to highlight upon the multi-faceted utility of FUE technique in various dermatological indications like androgenetic alopecia, alopecia areata, facial hair restoration, tractional alopecia, scarring alopecia, body hair transplant, vitiligo as well as hirsutism.

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“…Hair transplant comprises of harvesting hair from a donor area in the form of either a single strip or individual follicular units (Follicular unit extraction [FUE]) and grafting them into the recipient site. The availability of donor hair can sometimes be a limiting factor, but FUE offers the advantage of using hair from areas such as the beard, chest or other hairy sites when needed [5][6][7]. Hair transplant in cicatricial alopecia can be challenging owing to thin skin, lack of vasculature and sometimes subcutis also which otherwise is essential to hold the grafts and provides nutrients to transplanted follicles [6].…”

Section: Hair Transplantation In Cicatricial Alopeciamentioning

confidence: 99%

Follicular Unit Extraction (FUE) Hair Transplantation in Combination with Platelet Rich Plasma for the Treatment of Scarring Alopecia: A Case Series

Garg¹,

Pandya²,

Bhatt³

2019

Arch Clin Med Case Rep

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Objective: To study the effect of addition of platelet rich plasma (PRP) to the hair transplantation for scarring alopecia.Methods: An evaluation of the patients with detailed history, clinical examination and laboratory investigations was done. Routine baseline investigations and skin biopsy were done in order to rule out any activity of the underlying disease process. Freshly prepared Platelet rich plasma (PRP) using YCELL BIO kit was injected in freshly done slits over recipient area.Results: A total of 4 cases were studied-A 26 years old male with cleft lip surgical scar with absent hair growth on the middle third of the upper lip, a 22 year old male with a 5 year old post traumatic depressed scar over the junction of medial and lateral third of the right eyebrow, a 17 year old boy with a post burn scar over his left upper lip and adjoining lower cheek area and a 55 years old post menopausal female, an already diagnosed and treated case of frontal fibrosing alopecia (FFA). Hair transplantation was performed with follicular unit extraction (FUE). Freshly prepared PRP was injected intradermally after creating the slits. In all the cases, there was a good survival rate of the healthy hair follicles, accompanied by improvement in the texture of the surrounding skin.Conclusions: Platelet rich plasma, being a cocktail of growth factors, can bring vitality to the tissue and improve its vascularity, thus making it more receptive to the transplant. Additionally, with the improved vascularity of the recipient bed and activated fibroblasts, there is accelerated hair growth and better cosmetic outcomes of the scar.

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The Role of Hair Restoration Surgery in Primary Cicatricial Alopecia

Cited by 20 publications

References 14 publications

The assessment of hair transplantation outcomes in cicatricial alopecia

The assessment of hair transplantation outcomes in cicatricial alopecia

Follicular Unit Extraction [FUE] – One Procedure, Many Uses

Follicular Unit Extraction (FUE) Hair Transplantation in Combination with Platelet Rich Plasma for the Treatment of Scarring Alopecia: A Case Series

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