The role of herbal medicines in health care quality and the related challenges

Kityania

et al. 2023

Asian J Pharm Clin Res

Our health-care system would be incomplete without the use of medicinal herbs. In the days before modern medicine, several communities created medical knowledge systems known as “traditional medicine,” “indigenous medicine,” or “folk medicine.” The medicinal properties of plants and plant-based products are widely accepted. There are a variety of medical approaches available across the world, including allopathic, homoeopathic, Ayurvedic, and Chinese. The developed communities each have their own Materia Medica, which compiles thorough data on many plants used as medicines. According to current estimations from the field of botany, there are somewhere between 2,50,000 and 3,50,000 distinct plant species in existence. It is estimated that 35,000 unique species are used to cure a wide range of ailments in diverse places throughout the world. Based on general popularity among all ages, phytopharmaceuticals are an integral part of worldwide business and the global economy. According to a globe news wire study, the global herbal medicine market is estimated to be 550 billion dollars by 2030, up from 83 billion dollars in 2019. China and India lead the global herb market. China exports 120,000 tonnes of herbal remedies annually, followed by India with 32,000 tonnes. Europe is the world’s largest importer of medicinal plants (MP), taking in over 400,000 tonnes annually to fulfill local demand. In this review, we have discussed about the MP and their economic importance in global market.

Section: Mp and Human Healthmentioning

confidence: 99%

An Extensive Review on Medicinal Plants in the Special Context of Economic Importance

Kityania

et al. 2023

Asian J Pharm Clin Res

Asian Pac J Cancer Prev

“…Medicinal plants have been proven to be an alternative approach for treating various health conditions. Although synthetic drugs have taken traditional healing to some degree, the revival and attention of herbal medicines are very important (Mirzaeian et al, 2021). Medicinal plants are affordable and eco-friendly, with fewer side effects than synthetic drugs.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity Activity, Metabolite Profiling, and Isolation Compound from Crude Hexane Extract of Cleome rutidospermae

Yasir,

Rahim,

Lallo

et al. 2023

Objective: This study isolated the chemical compounds and evaluated the cytotoxic activity of the crude hexane extract of Cleome rutidospermae herb (CRH). Methods: The isolate was purified using silica gel, column chromatography, and preparative thin layer chromatography (PTLC). Furthermore, the structure of the compounds was identified by spectroscopic methods using 1D, 2D NMR, and mass spectrometry. The cytotoxic activity of CRH at a concentration of 20 ug/mL was also tested against MCF-7, A549, KB, KB-VIN, and MDA-MB-231 cancer cells using the sulforhodamine B (SRB) method. Results: The CRH contained compounds of unsaturated fatty acid, saturated fatty acid, lipid, glycerol, ω-3 fatty acid, and cholesterol. Two compounds were obtained from the plant, and their structures were identified as (1) Stigmasta-5,22-dien-3-ol (STML) and (2) 1,2-Benzene dicarboxylic acid, 1,2-bis (2-Ethylhexyl) esters (DEHP). These compounds were reported in this plant for the first time. In comparison, CRH had % growth inhibition in the proliferation of MCF-7 cells up to 28.1%, with cancer cells A549, KB, KB-VIN, and MDA-MB-231 by >50% Compared to the negative DMSO of 0.20%, while the positive control could inhibit the growth of all cancer cells (100%). Conclusion: Our findings suggested that crude herb from the plant CRH was the potential for breast cancer treatment.

“…Medicinal plants play an essential role in human and animal health care due to diverse biologically active compounds (5). Most people prefer plant-based medications over synthetic ones because they are more readily available, have low side effects, and are easier to administer (6).…”

Section: Introductionmentioning

confidence: 99%

Bioactivities, physicochemical parameters and GC/MS profiling of the fixed oil of Cucumis melo L seeds: A focus on anti-inflammatory, immunomodulatory, and antimicrobial activities

El-Anssary

Raoof

Saleh

et al. 2021

J Herbmed Pharmacol

Introduction: Recently, the recovery of waste products from plants as a source of biologically active compounds has increased interest. Therefore, the current research aims to evaluate the anti-inflammatory, immunomodulatory and antimicrobial activities of the fixed oil of Cucumis melo L seeds, as well as to investigate its physicochemical parameters and chemical composition. Methods: Anti-inflammatory activity was examined using carrageenan-induced rat paw edema assay. The antimicrobial activity was assayed against Staphylococcus aureus, Micrococcus luteus, Enterococcus faecalis, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans by well diffusion method. The chemical composition of the oil was determined by gas chromatography/mass spectrometry (GC/MS), α-tocopherol was estimated by high-performance liquid chromatography (HPLC). Results: Cucumis melo oil had no toxicity and possessed a promising anti-inflammatory activity. Moreover, the oil exhibited a reasonable decrease in the pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), and a significant increase in the anti-inflammatory cytokine (IL-10). The oil exhibited a reasonable antimicrobial activity against all tested organisms. The major identified compound in the unsaponifiable matter was (1-methyldodecyl) benzene (8.76%), while the major fatty acid was methyl linoleate (14.10%). The results of physicochemical characterization revealed the better quality of Cucumis melo oil. The amount of α-tocopherol in the oil was 23.5 μg/mL, which is considered a reasonable amount. Conclusion: These findings indicate that the fixed oil of Cucumis melo L seeds might be used as a safe natural anti-inflammatory, immunomodulatory and antimicrobial agent.