The role of imaging and molecular imaging in the early detection of metabolic and cardiovascular dysfunctions

Montet-Abou, Karin; Viallon, Magalie; Hyacinthe, Jean-Noël; Delattre, Bénédicte; Vallée, Jean‐Paul; Didier, Dominique; Croisille, Pierre; Montet, Xavier

doi:10.1038/ijo.2010.242

Cited by 6 publications

(3 citation statements)

References 117 publications

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“…2,21 We cannot rule out that resistin and other mediators secreted locally by adipocytes and activated macrophages may promote local effects on the aorta that are not measurable in the systemic circulation. Efforts to understand the effect of local mediators via molecular imaging techniques 22 and other methods warrant further investigation.…”

Section: In the Context Of The Current Literaturementioning

confidence: 99%

Periaortic Adipose Tissue and Aortic Dimensions in the Framingham Heart Study

Thanassoulis

Massaro

Corsini

et al. 2012

JAHA

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BackgroundPeriaortic fat, because of its contiguity with the aorta, may promote vascular remodeling and aortic dilatation. However, the relations between perioartic fat depots and aortic dimensions have not been previously described.Methods and ResultsA total of 3001 individuals (mean age 50±10 years, 49% women) from the Framingham Offspring and Third Generation cohorts underwent computed tomography for quantification of periaortic fat and aortic dimensions. We estimated the association between quantitative periaortic and visceral adipose tissue volumes (per standard deviation [SD] increment of volume) with aortic dimensions in both the thorax and abdomen. Thoracic periaortic fat was associated with higher thoracic aortic dimensions (β coefficient per SD of fat volume 0.67 mm, 95% confidence interval 0.58 to 0.76 mm; P<0.001). The association persisted after adjustment for age, sex, and cardiovascular risk factors including body mass index and visceral adipose tissue volume. Results for the association of periaortic fat and abdominal aortic dimensions were similar. Further adjustment for adipokines (resistin and adiponectin) had no significant impact on these associations.ConclusionsPeriaortic fat volume was associated with aortic dimensions in both the thorax and abdomen, supporting the notion that local fat depots may contribute to aortic remodeling. Further work to understand the mechanisms underlying this association is warranted.

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Section: In the Context Of The Current Literaturementioning

confidence: 99%

Periaortic Adipose Tissue and Aortic Dimensions in the Framingham Heart Study

Thanassoulis

Massaro

Corsini

et al. 2012

JAHA

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“…The evaluation of cardiac function using cardiac magnetic resonance imaging (if available) could be an option for individuals with extreme obesity. 8…”

Section: Airway Managementmentioning

confidence: 99%

“…Of note, assessment of cardiac function may be particularly difficult using transthoracic echocardiography. The evaluation of cardiac function using cardiac magnetic resonance imaging (if available) could be an option for individuals with extreme obesity 8 …”

Section: Pathophysiology Of Obesity and Surgical Managementmentioning

confidence: 99%

Child and Adolescent Bariatric Surgery in an Urban Tertiary Center: Special Anesthetic Considerations for Obesity

Vaughns,

McCullough‐Roach,

Williams

et al. 2023

The Journal of Clinical Pharma

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Children and adolescents with obesity who present for weight loss surgery are a unique subset of patients. A thorough understanding of the perioperative needs of these individuals is essential to avoid deleterious complications. This review illustrates the necessity for specialized care, including the continued need of specified drug dosing and a systematic approach in the management of the pediatric bariatric patient.

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