Objective
To reveal the risk factors that can lead to a complicated course and an
increased morbidity in patients < 1 year old after surgical ventricular
septal defect (VSD) closure.
Methods
We reviewed a consecutive series of patients who were admitted to our
institution for surgical VSD closure who were under one year of age, between
2015 and 2018. Mechanical ventilation (MV) time > 24 hours, intensive
care unit (ICU) stay longer than three days, and hospital stay longer than
seven days were defined as “prolonged”. Unplanned reoperation, complete
heart block requiring a permanent pacemaker implantation, sudden circulatory
arrest, and death were considered as significant major adverse events
(MAE).
Results
VSD closure was performed in 185 patients. The median age was five (1-12)
months. There was prolonged MV time in 54 (29.2%) patients. Four patients
(2.2%) required permanent pacemaker implantation. Hemodynamically
significant residual VSD was observed in six (3.2%) patients. Extracorporeal
membrane oxygenation-cardiopulmonary resuscitation was performed in one
(0.5%) patient. Small age (< 4 months)
(
P
-value<0.001) and prolonged cardiopulmonary bypass
time (
P
=0.03) were found to delay extubation and to prolong
MV time. Low birth weight at the operation was associated with MAE
(
P
=0.03).
Conclusion
Higher body weight during operation had a reducing effect on the MAE
frequency and shortened the MV duration, ICU stay, and hospital stay. As a
conclusion, for patients who are scheduled to undergo VSD closure, body
weight should be taken into consideration.