The role of laboratory processing in determining diagnostic conclusiveness of breast fine needle aspirations: conventional smearing versus a monolayer preparation

Wauters, C. A. P.; Kooistra, Bauke W; Strobbe, Luc J. A.

doi:10.1136/jcp.2009.066589

Cited by 11 publications

(3 citation statements)

References 32 publications

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“…The resultant mixture was collected in a container and then put on a poly-L-lysine slide (Menzel GmbH, Braunschweig, Germany). By centrifuging for 5 min at 688 rpm, the sediment was pressed onto the slide, creating a monolayer arrangement of all cells within a 12 mm diameter area [12,13]. The liquid based preparation slides were Papanicolaou-stained (Fig.…”

Section: Cwc Techniquementioning

confidence: 99%

“…The percentage of cases with a CWC diagnosis inadequate was comparable in the clinical and preclinical study (4.0% vs. 6,6%). As we stated in the preclinical study, it is important to note that the quality of the results on CWC are for a major part determined by factors such as the experience of the pathologists, the nature and the quality of the collecting medium, the standardised handling of the material by the technicians, and the cytospin monolayer preparation [3,11,13].…”

Section: Modified Cwc Techniquementioning

confidence: 99%

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Modified core wash cytology (CWC), an asset in the diagnostic work-up of breast lesions

Wauters

Sanders-Eras

Heijden

et al. 2010

European Journal of Surgical Oncology (EJSO)

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Manuscript category Original Article Condensed AbstractThe modified core wash cytology procedure is a valuable tool for obtaining a rapid diagnosis from core needle biopsies of breast lesions. 2 AbstractAim: A quick and reliable preliminary diagnosis is essential in the management of a sameday breast clinic. In a preclinical study we developed an alternative method of core wash cytology (CWC). This study is an evaluation of this new CWC method introduced into the clinical setting.Methods: From April 2008 to April 2009, biopsies were taken from lesions in the breast.CWC was obtained from core needle biopsy (CNB) with a modified technique and classified into the categories: malignant, suspicious for malignancy, atypical, benign and inadequate.CWC and CNB diagnoses were correlated with the histopathology of subsequently obtained resection specimens. The sensitivity and specificity were calculated.Results: CWC was obtained from 226 breast lesions. In 167 of these cases subsequent resection of the lesion was performed revealing 149 carcinomas and 18 benign lesions.Of the 149 malignant cases, 136 were considered as either malignant or suspicious for malignancy by CWC, 7 as atypical, 4 as benign and 2 as inadequate. None of the 18 benign lesions were classified as suspicious or malignant on CWC. Eight out of 149 resected carcinomas were not recognized as malignant by histological analysis of the CNB, while 7 of these cases the CWC was considered malignant. The sensitivity and specificity were 97% and 100%, respectively. Conclusions:In the vast majority of patients the modified CWC technique can provide a quick and reliable diagnosis of malignant breast lesions. Furthermore, combining CWC with CNB histology can improve adequate, preoperative recognition of the malignant character of breast lesions.

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Section: Cwc Techniquementioning

confidence: 99%

Section: Modified Cwc Techniquementioning

confidence: 99%

Modified core wash cytology (CWC), an asset in the diagnostic work-up of breast lesions

Wauters

Sanders-Eras

Heijden

et al. 2010

European Journal of Surgical Oncology (EJSO)

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“…El bloque celular es útil para efectuar estudios complementarios y una reserva de material para posibles estudios futuros. En cuanto a la PAG, está basada en sistemas de corte al vacío, obteniendo cilindros celulares con mayor muestra citológica, recomendado en nódulos de características predominantemente sólidas, para diagnóstico histológico (8).…”

Section: Introductionunclassified

Experiencia de la utilización de la punción ecoguiada en pacientes portadores de nódulos mamarios

Padrón Sanabria.

2023

RSOGV

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Objective: To describe the experience achieved by the Surgery Service of the National General Hospital “Dr. Ángel Larralde” in terms of the study of patients with breast nodules, through the use of ultrasound-guided punctures during the period January 2020 – November 2022. Methods: Observational-descriptive study, with a non-experimental, prospective, cross-sectional design. A deliberate nonprobabilistic sample of 138 patients was conducted. Breast ultrasound, fine needle puncture or core needle puncture were performed, depending on the type of lesion. The technique used was correlated with the diagnosis. Results: An average age of 46.72 ± 2.33 years was recorded; Females predominated (91.30%). The most frequent ultrasound finding was nodules in BI-RADS 4-A (30.43%). High percentages of effectiveness were obtained in both puncture techniques: sensitivity, specificity, positive predictive value and negative predictive value: 100%. There were no complications. Conclusions: The experience developed performing ultrasound-guided punctures in the management of the breast nodule is a useful and feasible method, avoiding unnecessary excisional biopsies, with high sensitivity and specificity, and minimizing the risks of complications inherent to the procedure.

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Liquid-Based Cytology and Cell Block in Breast Lesions

Pinto,

Tse,

Tan

et al. 2023

Fine Needle Aspiration Cytology of the Breast

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The role of laboratory processing in determining diagnostic conclusiveness of breast fine needle aspirations: conventional smearing versus a monolayer preparation

Abstract: Patients presenting with breast lesions can more often be offered a same-day, conclusive cytopathological diagnosis when FNA are prepared by a manual MP processing technique.

Cited by 11 publications

References 32 publications

Modified core wash cytology (CWC), an asset in the diagnostic work-up of breast lesions

Modified core wash cytology (CWC), an asset in the diagnostic work-up of breast lesions

Experiencia de la utilización de la punción ecoguiada en pacientes portadores de nódulos mamarios

Liquid-Based Cytology and Cell Block in Breast Lesions

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