The Role of Magnesium in the Development of Cardiovascular Diseases and the Possibility of their Prevention and Correction with Magnesium Preparations (Part 1)

Abstract

The article is devoted to the influence of magnesium on the homeostasis of the body and, in particular, on the cardiovascular system. It describes the importance of the presence and effects of magnesium on various key processes and functions occurring in the body. The reasons for the lack of magnesium and ways to replenish it both in the natural way (eating, certain foods) and magnesium preparations are considered. The article provides examples of large randomized studies that prove the importance of the influence of normal magnesium levels on human health in general and on the state of the cardiovascular system. These studies show how magnesium deficiency increases the risk of cardiovascular diseases and how it can be reduced. It is also shown which trace elements and vitamins are closely related to magnesium metabolism, and how they (in particular, potassium and vitamin B6) improve and facilitate the normalization of magnesium levels. It is noted how comorbidity decreases with the normalization of magnesium level – the higher the magnesium level in the blood plasma (closer to the upper limit and more), the less comorbidity and longer life expectancy. Magnesium is an absolutely essential ion and a good medicine. Magnesium deficiency and hypomagnesemia are quite common, difficult to diagnose (due to underestimation and rare level control) and accompany many diseases of the cardiovascular system and beyond. The widespread use of organic magnesium salts would improve the situation as a whole, due to their universal multiple effect on many processes in the body. This is an integral part of therapeutic and preventive measures in patients with already existing diseases and in people who do not have diseases, but who are at risk due to existing hypomagnesemia.

Sympathetic hyperactivity in patients with hypertension: pathogenesis and treatment. Part II

“…Дефицит магния приводит к повышению АД, увеличению активности СНС и многим другим сердечно-сосудистым заболеваниям, что доказано многочисленными исследованиями (для обзора см. [62,63]).…”

Physicochemical, Biochemical, Pharmacological Properties of Magnesium

“…The magnesium content in cerebrospinal fluid correlates with the magnesium content in erythrocytes, and the magnesium content in the pituitary gland determines the ability to memorize, which is somehow related to DNA structure. Studies focusing on determining magnesium levels in cells and intercellular fluid have established its direct influence on human health [17]. Magnesium deficiency is often associated with deficiencies in potassium, copper, zinc, and less commonly chromium, cobalt, or nickel in blood serum.…”