The role of medicinal cannabis in clinical therapy: pharmacists’ perspectives

Isaac, Sami; Saini, Bandana; Chaar, Betty

doi:10.1016/j.sapharm.2016.05.067

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…Pharmacists are particularly central to the process because they have the training to assess and corroborate the appropriateness and safety of the use of cannabinoids through their access not only to the patient's electronic medical record, but also to advanced database tools capable of assessing potential drug-drug interactions and cytochrome P450 interactions 81,82 . Furthermore, pharmacies are designed to ensure proper storage and security of medical products.…”

Section: The Importance Of Inter-professional Collaborationmentioning

confidence: 99%

A User’s Guide to Cannabinoid Therapies in Oncology

Maida

Daeninck

2016

Current Oncology

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ABSTRACT"Cannabinoid" is the collective term for a group of chemical compounds that either are derived from the Cannabis plant, are synthetic analogues, or occur endogenously. Although cannabinoids interact mostly at the level of the currently recognized cannabinoid receptors, they might have cross reactivity, such as at opioid receptors.Patients with malignant disease represent a cohort within health care that have some of the greatest unmet needs despite the availability of a plethora of guideline-driven disease-modulating treatments and pain and symptom management options. Cannabinoid therapies are varied and versatile, and can be offered as pharmaceuticals (nabilone, dronabinol, and nabiximols), dried botanical material, and edible organic oils infused with cannabis extracts. Cannabinoid therapy regimens can be creative, involving combinations of all of the aforementioned modalities. Patients with malignant disease, at all points of their disease trajectory, could be candidates for cannabinoid therapies whether as monotherapies or as adjuvants.The most studied and established roles for cannabinoid therapies include pain, chemotherapy-induced nausea and vomiting, and anorexia. Moreover, given their breadth of activity, cannabinoids could be used to concurrently optimize the management of multiple symptoms, thereby reducing overall polypharmacy. The use of cannabinoid therapies could be effective in improving quality of life and possibly modifying malignancy by virtue of direct effects and in improving compliance or adherence with disease-modulating treatments such as chemotherapy and radiation therapy.

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Section: The Importance Of Inter-professional Collaborationmentioning

confidence: 99%

A User’s Guide to Cannabinoid Therapies in Oncology

Maida

Daeninck

2016

Current Oncology

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“…The use of Cannabis sativa L. (cannabis; ssp sativa and indica) has been suggested as a treatment for a variety of medical conditions in recent reviews, including chronic pain, asthma, nausea associated with chemotherapy, multiple sclerosis and glaucoma. [1][2][3][4] Phytocannabinoids are putatively believed to be the primary bioactive constituents, although terpenes and flavonoids may also contribute to the overall bioactivity of cannabis. 1 A subset of the more than 100 phytocannabinoids found in cannabis 5 have demonstrable biological effects.…”

Section: Introductionmentioning

confidence: 99%