In order to improve the total dose radiation hardness of the buried oxides(BOX) of separation by implanted oxygen(SIMOX) silicon on insulator (SOI),we implanted silicon into the BOX at a dose of 1×1015cm-2 and then annealed at 800 in N2 ambience. Partially depleted CMOS/SOI inverters with enclosed-gate structure fabricated on improved SIMOX substrate and standard SIMOX substrate were exposed to 60Co -ray radiation. The results of demonstrate that compare to standard CMOS/SOI inverters; the improved CMOS/SOI inverters have less switching voltage shifts and smaller leakage current after the same total dose irradiation.