The Role of Nasal Allergy in Otitis Media with Effusion: A Clinical Study

Tomonaga, Kazuhiro; Kurono, Yuichi; Mogi, Goro

doi:10.3109/00016488809125100

Cited by 91 publications

(66 citation statements)

References 16 publications

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“…1b, 2). Other investigators, using objective intradermal and in vitro testing, have demonstrated that 72-100% of the children with OME are atopic: Tomonaga (72%) [26], Nsouli (78%) [27], Hurst (81%) [28], McMahan (93%) [29], Hall (100%) [30]. Statistical analysis evidenced a significant correlation between atopy and OME with a correlation index of r = 0.998 (v 2 = 54.56; P = 1.50 -13 ; OR = 11.16).…”

Section: Resultsmentioning

confidence: 99%

The role of atopy in otitis media with effusion among primary school children: audiological investigation

Martines

Martinciglio

Martines

et al. 2010

Eur Arch Otorhinolaryngol

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The objective of this study was to evaluate the role of atopy in otitis media with effusion (OME) in children attending primary school in western Sicily focusing on the audiological characteristics among atopic and nonatopic subjects suffering from OME. A total of 310 children (5-6 years old) were screened by skin tests and divided into atopics (G1) and non-atopics (G2). The samples were evaluated for OME by pneumatic otoscopy, tympanogram and acoustic reflex tests. The parameters considered were: documented persistent middle ear effusion by otoscopic examination for a minimum of 3 months; presence of B or C tympanogram; absence of ipsilateral acoustic reflex and a conductive hearing loss greater than 25 dB at any one of the frequencies from 250 Hz through 4 kHz. A total of 56 children (18.06%) resulted to be atopics while 254 were non-atopics. OME was identified in 24 atopic children and in 16 non-atopic children for a total number of 40 children; the overall prevalence rate was 12.9% (42.85% for G1 and 6.30% for G2). OME was bilateral in 28 children (70%), with a significative difference between G1 (79.17%) and G2 (56.25%). The prevalence of B tympanogram was 70.59%, corresponding to 79.07% for G1 and 56% for G2. The mean air conduction pure tone was, respectively, 31.97 dB for G1 and 29.8 dB for G2. The prevalence value of OME in atopic children, also supported by the higher predominance of bilaterality, B tympanogram and hearing loss among this group, could suggest the important role of allergy in the pathogenesis of OME.

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Section: Resultsmentioning

confidence: 99%

The role of atopy in otitis media with effusion among primary school children: audiological investigation

Martines

Martinciglio

Martines

et al. 2010

Eur Arch Otorhinolaryngol

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“…6 In another study, 77 children who had chronic middle ear effusion, and who had had at least one ventilation tube placement performed were followed up. There was increased IgE in the middle ear effusion in 14 out of 32 children with allergic rhinitis, compared with two out of 45 children considered to be non-allergic.…”

Section: Resultsmentioning

confidence: 99%

Fatores de risco para otite média aguda recorrente: onde podemos intervir? - uma revisão sistemática da literatura

Neto

Hemb²,

Silva³

2006

J. Pediatr. (Rio J.)

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Objective: Review evidence about modifiable risk factors for recurrent acute otitis media.Source of data: MEDLINE with no language restriction, from January 1966 to July 2005, using descriptors acute otitis media/risk factors. Two hundred and fifty-seven articles were obtained. These included randomized clinical trials, cohorts, case-control and cross-sectional studies that contained analyses of modifiable risk factors for the development of recurrent acute otitis media as the main objective and with samples of individuals up to the age of 18 years. Except when relevant, the following were excluded: non-systematic reviews, reports of cases, series of cases, and medical society guidelines. Summary of data:Nine risk factors linked to the host and eight linked to the environment were identified. Of the first group, allergy, craniofacial abnormalities, gastroesophageal reflux and the presence of adenoids were classified as modifiable. In the second category, upper airway infections, day care center attendance, presence of siblings/family size, passive smoking, breastfeeding and use of pacifiers were included. Afterwards, the risk factors were classified in accordance with levels of evidence. Conclusions:The risk factors established for recurrent acute otitis media and capable of being modified were the use of pacifiers and care in daycare centers. The probable risk factors were privation of mothers milk, presence of siblings, craniofacial abnormalities, passive smoking and presence of adenoids. No modifiable factor was classified as unlikely. Among those that need further study are allergy, gastroesophageal reflux and passive smoking during gestation. J Pediatr (Rio J)

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“…But, OME is the most frequent cause of hearing loss in children Shekelle et al, 2002). An epidemiologic link between OME and AR has been demonstrated in many trials (Alles et al, 2001;Tomonaga et al, 1988). Prevalence of AR among patients with chronic or recurrent OME is higher than that seen in the same age group in the general population.…”

Section: Fig 3 Sinus Cycle Leading To Rs (Adapted Frommentioning

confidence: 98%