Fax: (0711) 6856842The detailed study of the role of air pressure in deep hole drilling by femtosecond and picosecond intense laser pulses (Ti:A1203 and Nd:YAP lasers) was performed in the range 1÷1000 mBar. Steel sample plates were mostly tested, experimental data obtained for ceramic materials is also presented. The following ablation parameters were measured and analyzed: ablation rates and their dependence on the channel depth, ablated crater morphology, optical transmission in channels after through hole formation. Both percussion and helical drilling regimes were used.Special attention was paid to two strong gas assisted effects typical of sub-picosecond and subnanosecond material ablation, which are low threshold gas breakdown in deep channels and nonlinear interaction of ultra-short intense pulses with air resulting in conical emission. Unwanted aspects of both phenomena were shown to disappear in a moderate vacuum of lOO mBar. A new approach to formation of such a vacuum in drilled channels was also proposed and experimentally modeled using ultra-high repetition rate nanosecond laser pulses.Keywords: laser ablation in air and vacuum, ultra-short pulses, deep channels, air breakdown, white light continuum generation, ultra-high repetition rate laser exposure