The role of pyrimidine and water as underlying molecular constituents for describing radiation damage in living tissue: A comparative study

Abstract

Water is often used as the medium for characterizing the effects of radiation on living tissue. However, in this study, charged-particle track simulations are employed to quantify the induced physicochemical and potential biological implications when a primary ionising particle with energy 10 keV strikes a medium made up entirely of water or pyrimidine. Note that pyrimidine was chosen as the DNA/RNA bases cytosine, thymine, and uracil can be considered pyrimidine derivatives. This study aims to assess the influence of the choice of medium on the charged-particle transport, and identify how appropriate it is to use water as the default medium to describe the effects of ionising radiation on living tissue. Based on the respective electron interaction cross sections, we provide a model, which allows the study of radiation effects not only in terms of energy deposition (absorbed dose and stopping power) but also in terms of the number of induced molecular processes. Results of these parameters for water and pyrimidine are presented and compared.

Theoretical Formalism To Estimate the Positron Scattering Cross Section

“…Chiari et al 9 There are several studies reported fore + -N 2 scatteringin the literature [12][13][14][15][16][17][18][19][20][21][22][23] . Similarly for O 2 , there exist previous experimental results from Marler et al 5 , Katayama et al 24 and Dababneh et al 25 and theoretical results from De-Heng et al 26 and Raj 27 . Thus, it is quite evident that N2and…”

The electron-furfural scattering dynamics for 63 energetically open electronic states

“…[4][5][6][7][8] The present submission is a new step in this series of investigations with furfural, and as it is the integral cross sections (ICSs) that are generally of most interest to the modelling communities [9][10][11][12][13][14] it therefore represents an important achievement. Note that this follows on from a similarly extensive study on phenol, [15][16][17][18][19][20] another important by-product from the application of atmosphericpressure plasmas to biomass.…”

Integral elastic, electronic-state, ionization, and total cross sections for electron scattering with furfural

“…[4][5][6][7][8] The present submission is a new step in this series of investigations with furfural, and as it is the integral cross sections (ICSs) that are generally of most interest to the modelling communities [9][10][11][12][13][14] it therefore represents an important achievement. Note that this follows on from a similarly extensive study on phenol, [15][16][17][18][19][20] another important by-product from the application of atmosphericpressure plasmas to biomass.…”