Sexual assault (defined as sexual relations with another person obtained through physical force, threat, or intimidation) of children includes genital fondling, photographing, or viewing for sexual gratification; exposure of the child to pornographic material or to adult sexual activity; and attempted or successful penetration of any of the child's orifices. The purpose of this investigation was to review the medical literature published since 1988 that reported on the prevalence of particular sexually transmitted diseases (STDs) in populations of sexually assaulted adults and adolescents and sexually abused children, as well as the prevalence of sexual abuse among children who present with an STD. These data will be helpful for managing cases of sexual assault involving children, adolescents, or adults; estimating the risk of abuse among children with specific STDs; and identifying research priorities in this area.