The role of taurine in adaptation of visceral systems under psycho-emotional stress in rats

Avetisyan, É. A.; Petrosyan, A.M.; Khachiyan, M S; Saakyan, N. A.; Simonyan, L. Yu.; Shogheryan, S. A.

doi:10.1134/s0022093017010045

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…At the basis of neurobiological models, and models related to personality traits, it is possible to look for genetic changes, which may determine among the others things overactivity of the central nervous system, and, consequently, changes in behavior or emotional reactions [19].…”

Section: Introductionmentioning

confidence: 99%

Initial Study on COMT and DRD2 Gene Polymorphisms as Well as the Influence of Temperament and Character Trait on the Severity of Alcohol Craving in Alcohol-Dependent Patients

Czarnecki

Ziółkowski

Chodkiewicz

et al. 2021

JCM

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The main aim of this work was to determine the impact of COMT and DRD2 gene polymorphisms together with temperament and character traits on alcohol craving severity alcohol-dependent persons. The sample comprised of 89 men and 16 women (aged 38±7). For the sake of psychological assessment various analytic methods have been applied like the Short Alcohol Dependence Data Questionnaire (SADD), Penn Alcohol Craving Scale (PACS) or Temperament and Character Inventory (TCI) test. The SNP polymorphism of the analyzed genes was determined by Real Time PCR test. The results showed, that the COMT polymorphismmay have an indirected relationship with the intensity and changes in alcohol craving during abstinence. The DRD2 receptor gene polymorphisms are related with the intensity of alcohol craving. It seems that the character traits like “self-targeting”, including “self-acceptance”, are more closely related to the severity of alcohol craving and polymorphic changes in the DRD2 receptor than temperamental traits. Although this is a pilot study the obtained results appeared to be promising and clearly indicate the link betweengene polymorphisms alcohol craving and its severity.

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Section: Introductionmentioning

confidence: 99%

Initial Study on COMT and DRD2 Gene Polymorphisms as Well as the Influence of Temperament and Character Trait on the Severity of Alcohol Craving in Alcohol-Dependent Patients

Czarnecki

Ziółkowski

Chodkiewicz

et al. 2021

JCM

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The Relationship of the Ratio Taurine/Alanine in Serum and Indicators of Heart Rate Variability in Patients With Postinfarction Cardiosclerosis and Diabetes Mellitus Type 2

Belikova¹

2019

USMYJ

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The aim of the article : to determine the relationship of the ratio taurine/alanine (Tau/Ala) serum indicators of heart rate variability (HRV) in patients with postinfarction cardiosclerosis (PICS) and diabetes mellitus type 2 (DM 2). Materials and methods: we examined 87 patients with PICS and DM 2 – 50 women and 37 men, median age of the patients was 65.2 years (microtile interval 61-69 years). Amino acids were determined and the ratio between them. According to the results of Holter ECG monitoring (of HMCG) evaluated HRV. Results: in patients with PICS compared with healthy individuals observed a significant decrease in the blood levels of Tau/Ala (at 51.01%, p<0.001). The presence of comorbid diabetes is accompanied by more significant decrease in Tau/Ala (for the accounting period 82.22%, p<0.001) compared to healthy individuals. Between Tau/Ala and SDNN, LF, TP, VLF power of communication has been high, between Tau/Ala and RMSSD, HF, pNN 50.%, ULF, – moderate strength. Conclusions: the lower values of Tau/Ala in the blood of patients Pxs diabetes compared with patients without disorders of carbohydrate metabolism, accompanied by a decrease in spectral and temporal parameters of HRV, but that does not mean a causal relationship, may be associated with pathogenetic mechanisms of disorders of carbohydrate metabolism and requires further research.

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The role of taurine in adaptation of visceral systems under psycho-emotional stress in rats

Cited by 2 publications

References 10 publications

Initial Study on COMT and DRD2 Gene Polymorphisms as Well as the Influence of Temperament and Character Trait on the Severity of Alcohol Craving in Alcohol-Dependent Patients

Initial Study on COMT and DRD2 Gene Polymorphisms as Well as the Influence of Temperament and Character Trait on the Severity of Alcohol Craving in Alcohol-Dependent Patients

The Relationship of the Ratio Taurine/Alanine in Serum and Indicators of Heart Rate Variability in Patients With Postinfarction Cardiosclerosis and Diabetes Mellitus Type 2

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