The role of the <scp>University of Padua</scp> medical school in the study of conjoined twins between 18th and early 19th century

Magno, Giovanni; Kim, Yong‐Chul; Oostra, Roelof‐Jan; Zanatta, Alberto

doi:10.1002/ajmg.a.62938

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…The etiopathogenesis of monozygotic pregnancies is not clear (Magno et al, 2022). The classical theory, called “fission”, postulates that these twins would be the result of fission of the zygote, according to the moment in which this division occurs, the different varieties of chorion and amnion are produced: dichorionic, monochorionic, monoamniotic and conjoined.…”

Section: Discussionmentioning

confidence: 99%

Monochorionic triplet pregnancy complicated by conjoined twins and early twin–twin transfusion syndrome

Bustos,

Vera,

Ahumada

et al. 2024

Birth Defects Research

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BackgroundThe condition of monozygotic, monochorionic triplet fetuses with a pair of conjoined twins is extremely rare (close to one in a million births), presents challenges in its management, and with poor prognosis.Case reportWe report a case of monochorionic diamniotic triplet pregnancy, ultrasound at 14 weeks shows a pair of conjoined thoracopagus fetuses, sharing heart, liver, and umbilical cord, in addition to omphalocele. The third fetus, without malformations, presents signs of early heart failure compatible with twin‐to‐twin transfusion syndrome. It was decided to carry out expectant management where at 18 weeks, intrauterine death of the three fetuses occurs. An abortion is performed by hysterotomy.ConclusionsThe treatment in these cases is discussed, three management options have been proposed: expectant management, selective reduction of the conjoined fetuses, or termination of the pregnancy. A review of the literature found only 12 cases with this combination of pathologies, in which only 3 normal fetuses (25%) survived and none of the conjoined twins survived. To our knowledge, this case is the first of a monochorionic triplet pregnancy with conjoined fetuses complicated with early twin‐to‐twin transfusion.

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Section: Discussionmentioning

confidence: 99%

Monochorionic triplet pregnancy complicated by conjoined twins and early twin–twin transfusion syndrome

Bustos,

Vera,

Ahumada

et al. 2024

Birth Defects Research

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“…In the 1860s, Brunetti founded the Museum of Pathological Anatomy of the University of Padua, recently renovated in 2018 and dedicated to the figure of Giovanni Battista Morgagni (1682–1771). The Museum still collects the original preparations created by Brunetti for teaching and studying anatomy and pathology, preserved dry, in liquid and with the original method of artificial mummification he invented, the so‐called tannization, considered Brunetti's main scientific contribution (Magno, Boer, et al, 2022; Monza et al, 2019; Zanatta & Zampieri, 2018).…”

Section: Introductionmentioning

confidence: 99%

The tannization of human tissues: A nineteenth‐century educational preservation technique at the Morgagni Museum

Magno,

Beck De Lotto,

Zampieri

et al. 2023

Curator The Museum Journal

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Lodovico Brunetti (1813–1899), professor of pathological anatomy at the University of Padua and founder of the Museum of Pathological Anatomy, believed that anatomical preparations were essential for the practice and teaching of pathological anatomy. At his arrival in Padua in 1855, there were around 300 made by other professors of medicine, including some by Giovanni Battista Morgagni, preserved either in liquid or dry. These conservation methods did not satisfy Brunetti, as they drastically altered the shape of the anatomical pieces (reduced by mummification and dilated in liquid); thus, he decided to create a new method called “tannization,” for the use of tannic acid. Brunetti's new method was based on dissection and injection techniques, and it had the substantial advantage of maintaining unchanged the shape and texture of the anatomical specimens, even microscopically, as well as being not so expensive. Another important advantage consisted in the fact that the different stages of the preparation could be put into practice even at different times and at a considerable distance from each other. His specimens seemed to be mummified, but they maintained a remarkable elasticity and softness, as well as almost completely unaltered proportions. Today, the Morgagni Museum of the University of Padua still preserves several tannized preparations attributable to Brunetti and his successors. The current study aims to show the educational value of this method showing the results of Brunetti's tannization nowadays.

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The role of the University of Padua medical school in the study of conjoined twins between 18th and early 19th century

Magno

Kim

Oostra

et al. 2022

American J of Med Genetics Pt A

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The Medical School of Padua (Italy) contributed profoundly to the study of teratology. Many famous physicians and professors of medicine, such as Liceti, Vallisneri, Morgagni, and Malacarne, have studied and investigated these anomalies to better understand the causes and to find a potential explanation, often preserving the specimens for future studies. The present study highlights some historical cases of conjoined twins and a conjoined triplet preserved at the Morgagni Museum of Human Anatomy to show the development of medical theories in the teratological field between the 18th and early 19th century. This approach will provide insights into different study methods and ideas of some of the most famous scholars working in Padua at that time. The current article focuses on rare cases, both human and animal, that were encountered by physicians who worked in the Veneto area in the late 18th and early 19th century. Their detailed descriptions are not only of historical but also of contemporary dysmorphological value.

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The role of the University of Padua medical school in the study of conjoined twins between 18th and early 19th century

Cited by 5 publications

References 16 publications

Monochorionic triplet pregnancy complicated by conjoined twins and early twin–twin transfusion syndrome

Monochorionic triplet pregnancy complicated by conjoined twins and early twin–twin transfusion syndrome

The tannization of human tissues: A nineteenth‐century educational preservation technique at the Morgagni Museum

The role of the University of Padua medical school in the study of conjoined twins between 18th and early 19th century

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