The role of the sympatho‐adrenal system in the control of sweating in the ox (Bos taurus).

Findlay, J. D.; Robertshaw, David

doi:10.1113/jphysiol.1965.sp007663

Cited by 45 publications

(19 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The position of the electrodes was verified at autopsy. In the two remaining animals a bilateral adreno-medullary denervation had been performed approximately 6 months before the first experiment by the technique described by Findlay & Robertshaw (1965). All surgical operations were performed aseptically under 'Fluothane' (2-bromo-2-chloro-1,1,1 -trifluorethane, I.C.I.…”

Section: Methodsmentioning

confidence: 99%

“…ROBERTSHA W AND G. C. WHITTOW INTRODUCTION The increase in the concentration of glucose and lactic acid in the blood and the cardiovascular changes which occur in the unanaesthetized ox during hyperthermia (Bianca & Findlay, 1962;Whittow, 1965) are consistent with an increased sympatho-adrenal activity at elevated deepbody temperatures. However, evidence for an increased sympatho-adrenal activity during hyperthermia in other species is conflicting (Hartman & Hartman, 1923;Symbas, Jellinek, Cooper & Hanlon, 1964) and, as a result of their investigation of the adrenergic sudomotor mechanism of the ox, Findlay & Robertshaw (1965) concluded that mild hyperthermia was not associated with any adreno-medullary stimulation although the sweat glands appear to require an intact nerve supply. Furthermore, although the effects of hyperthermia in the ox can be simulated to a large extent by localized heating of the anterior hypothalamus and preoptic region alone (Ingram & Whittow, 1962aIngram, McLean & Whittow, 1963;Whittow, 1965), it is known that localized heating of this area of the brain in the unanaesthetized goat, another ruminant animal, does not result in an increase in the urinary excretion of catecholamines (Andersson, Gale, Hokfelt & Ohga, 1963).…”

mentioning

confidence: 99%

See 1 more Smart Citation

The effect of hyperthermia and localized heating of the anterior hypothalamus on the sympatho‐adrenal system of the ox (Bos taurus)

Robertshaw¹,

Whittow²

1966

The Journal of Physiology

View full text Add to dashboard Cite

4. Bilateral adreno-medullary denervation abolished the changes in plasma catecholamine levels associated with hyperthermia.5. Localized heating of the anterior hypothalamus in either a cool or a warm environment did not result in any change in plasma catecholamine levels.6. It was concluded that the source of the increased levels of plasma catecholamines during hyperthermia was the adrenal medulla and that the stimulus for their release was a nervous one rather than direct chemical or thermal stimulation of the adrenal medulla. The cause of the increased sympatho-adrenal activity was not apparent, but neither thermal stimulation of cutaneous and hypothalamic receptors nor the associated changes in respiratory activity seemed to be implicated in the response.

show abstract

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

The effect of hyperthermia and localized heating of the anterior hypothalamus on the sympatho‐adrenal system of the ox (Bos taurus)

Robertshaw¹,

Whittow²

1966

The Journal of Physiology

View full text Add to dashboard Cite

show abstract

“…Sheep and goats show discrete discharges of moisture on to the surface of the skin (Bligh, 1961;Waites & Voglmayr, 1963;Robertshaw, 1968), and it appears that evaporative cooling from the skin is negligible in these species (Robertshaw, 1968). Although the sweat glands of domestic ruminants exhibit different patterns of activity they are all controlled by adrenergic sympathetic nerves (Findlay & Robertshaw, 1965;Robertshaw, 1968). Simpson (1945) The present experiments were designed to examine (1) the response of sweat glands to heat exposure, (2) the control of the sweat glands, and (3) a possible relationship between sweat gland activity and the phylogenetic position of the species.…”

Section: Introductionmentioning

confidence: 99%

A comparison of sweat gland activity in eight species of East African bovids

Robertshaw¹,

Taylor²

1969

The Journal of Physiology

View full text Add to dashboard Cite

SUMMARY1. The pattern and control of the sweat glands of eight species of wild bovids has been studied.2. Heat exposure resulted in changes in cutaneous moisture loss which showed considerable species variation. Duiker, Grant's gazelle, Thomson's gazelle and oryx all demonstrated periodic discharges of moisture on to the surface of the skin. Defassa waterbuck and eland exhibited discharges which were accompanied by a gradual rise in basal level. Buffalo showed an immediate large increase which was sustained during the period of heat exposure. Three wildebeest displayed small fluctuations whilst a fourth animal showed a step-wise increment in cutaneous moisture loss.3. The intravenous infusion of adrenaline into the buffalo and one wildebeest caused an increase in cutaneous moisture loss, the magnitude of which was directly related to the size of the dose administered. In three other wildebeest, and all other animals tested, a single injection of adrenaline was necessary to cause a discharge of moisture on to the surface of the skin. Noradrenaline was without effect.4. Heat-induced but not adrenaline-induced sweating was inhibited by the intravenous administration of an adrenergic neurone blocking agent, bethanidine. 5. It is concluded that the sweat glands of the wild bovids studied are under adrenergic neurone control, in common with the domestic bovids previously studied, and that there is no correlation between the pattern of sweating and the phylogenetic position of the species.

show abstract

“…Sweating in cattle is controlled by an adrenergic mechanism mediated by ex-receptors. Bethanidine blocks the release of adrenergic transmitter to the sweat glands and phenoxybenzamine blocks the receptor site (Findlay and Robertshaw 1965). Neither drug, although they both blocked the sweat response to heat exposure, suppressed the effect of lipid solvents.…”

Section: Discussionmentioning

confidence: 97%

“…It is considered that the increase in cutaneous moisture loss caused by heat exposure or intravenous adrenaline administration is due to stimulation of the sweat glands (Findlay and Robertshaw 1965). Either exposure to an air temperature of 40°C or a single intravenous injection of adrenaline (2· 5 flg/kg) will produce maximum sweating in cattle (Robertshaw, unpublished data).…”

Section: Discussionmentioning

confidence: 99%

Effect of Lipid Solvents on Cutaneous Moisture Loss

Hiley¹,

Pan²,

Robertshaw³

et al. 1977

Aust. Jnl. Of Bio. Sci.

Self Cite

View full text Add to dashboard Cite

Application of various lipid solvents and dimethyl sulphoxide to the skin of cattle, sheep, eland and African buffalo exposed to an air temperature of 20°C caused an increase in cutaneous moisture loss.The effect did not occur after exposure to an air temperature of 40°C or after adrenaline administration.Blockage of sweating by either bethanidine or phenoxybenzamine did not affect the response. Camel, donkey, dog and man showed no increase in cutaneous moisture loss after lipid solvent application to the skin.It is concluded that lipid solvents directly stimulate the secretory cells of the sweat glands of members of the family Bovidae and that this is not due to the release of transmitter substance nor to stimulation of adrenergic receptors, but is due to direct stimulation of the sweat glands themselves.

show abstract

The role of the sympatho‐adrenal system in the control of sweating in the ox (Bos taurus).

Cited by 45 publications

References 25 publications

The effect of hyperthermia and localized heating of the anterior hypothalamus on the sympatho‐adrenal system of the ox (Bos taurus)

The effect of hyperthermia and localized heating of the anterior hypothalamus on the sympatho‐adrenal system of the ox (Bos taurus)

A comparison of sweat gland activity in eight species of East African bovids

Effect of Lipid Solvents on Cutaneous Moisture Loss

Contact Info

Product

Resources

About