The role of ultrasonography in the diagnosis of fetal isolated complete agenesis of the corpus callosum: a long-term prospective study

Abstract

A dedicated neurosonographer could diagnose the iCACC with the same accuracy as MRI and in up to 90% of cases the newborn will have a regular development.

Counseling in fetal medicine: agenesis of the corpus callosum

“…Over 3600 titles and abstracts were reviewed. The search strategy, keywords used and results are found in Appendix S1 and the studies used in this Review are summarized in Appendices S2–S4.…”

Antenatal diagnosis of agenesis of the corpus callosum

“…This is particularly important in the context of ACC as researchers have found additional brain malformations in a high proportion of cases 3,25,26 and as high as 63% in one report. 4 This issue is not discussed in detail in the current paper because of the lack of reference outcome data for the associated brain abnormalities. Although iuMRI provides a reliable method for the reference diagnosis of ACC, that claim cannot be made for cortical formation abnormalities (such as polymicrogyria or heterotopia).…”

Agenesis of the corpus callosum: classifying functional manifestations with the ICF-CY

“…Majority of sample exhibited poor visual acuity, refractive errors, strabismus Cignini et al [2] n ¼ 13, congenital, complete ACC Stanford-Binet Typical psycho-motor and cognitive development in 92.3% of sample this process. The majority of meaningful concepts in the literature were most accurately mapped to the second-level chapter descriptors (e.g.…”

“…Children with agenesis of the corpus callosum have a highly variable clinical presentation. They may experience typical development, free from clinical impairment in any domain [2,9], or they may have severe impairment in multiple areas [10][11][12]. Common impairments include functional limitations of feeding, sleeping, motor development (specifically bimanual coordination), bilateral visual processing, attention, atypical sensory responses, phonological processing, understanding nonliteral language, interpreting social cues and comprehending emotions.…”

“…It begins to develop around the 12th week of gestation [1] and can be seen on a sonogram or fetal MRI by week 20 [2]. Agenesis of the corpus callosum (ACC) is a congenital condition in which the corpus callosum fails to develop fully, resulting in either the complete absence of the structure or the absence of substantial portions of the structure.…”