Language comprehension often involves the generation of predictions. It has been hypothesized that such prediction-for-comprehension entails actual language production. Recent studies provided evidence that the production system is recruited during language comprehension, but the link between production and prediction during comprehension remains hypothetical. Here, we tested this hypothesis by comparing prediction during sentence comprehension (primary task) in participants having the production system either available or not (non-verbal versus verbal secondary task). In the primary task, sentences containing an expected or unexpected target noun-phrase were presented during electroencephalography recording. Prediction, measured as the magnitude of the N400 effect elicited by the article (expected versus unexpected), was hindered only when the production system was taxed during sentence context reading. The present study provides the first direct evidence that the availability of the speech production system is necessary for generating lexical prediction during sentence comprehension. Furthermore, these important results provide an explanation for the recruitment of language production during comprehension.Recent studies have provided evidence for a potential role of production processes in language comprehension [1][2][3][4] , but what exactly is the link between production and comprehension is a central topic in language sciences and remains to be determined 5 . Based on several recent frameworks, this missing link could be prediction. Listeners constantly predict upcoming information during language comprehension (to facilitate comprehension and dialogue), and such predictions are accompanied by covert production [6][7][8][9] . Except some indirect support in the literature showing that language production skills (category fluency task, production vocabulary) and prediction are related 10-14 , there is no direct evidence so far that the production system is necessary for prediction during comprehension (see 15 for review). Providing experimental evidence for this claim would generate important knowledge regarding the production-comprehension link and consequently improve our understanding of the neurocognitive foundations of human communication.In the present study, we measured lexical prediction during sentence comprehension when taxing the production system. The rationale was that if production is mandatory for prediction, then prediction should vanish when the availability of the production system is reduced. This was done by preventing inner speech through articulatory suppression (AS; e.g., uttering a certain syllable repeatedly while completing the primary task 16 ). If performance on the primary verbal task relies on inner speech, it should be significantly impaired by AS because articulation of irrelevant information prevents subvocal rehearsal of the verbal input 17 . Lexical prediction can be measured through event-related potential (ERP) responses derived from electrophysiological recording during...