The <scp>O</scp>dense <scp>C</scp>hild <scp>C</scp>ohort: Aims, Design, and Cohort Profile

Kyhl, Henriette Boye; Jensen, Tina Kold; Barington, Torben; Buhl, Susanne; Norberg, Lene Annette; Jørgensen, Jan Stener; Jensen, Ditlev Frank Granhøj; Christesen, Henrik Thybo; Lamont, Ronald F.; Husby, Steffen

doi:10.1111/ppe.12183

Cited by 137 publications

(153 citation statements)

References 24 publications

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“…The Odense Child Cohort study is a population-based cohort study comprising pregnant women recruited between 1 January 2010 and 31 December 2012 (24). All women who were pregnant in the municipality of Odense during this time were eligible for participation, and 6707 women were approached directly with recruitment material.…”

Section: Methodsmentioning

confidence: 99%

Vitamin D insufficiency is associated with increased risk of first-trimester miscarriage in the Odense Child Cohort

Andersen

Jørgensen

Jensen

et al. 2015

The American Journal of Clinical Nutrition

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We found an association between 25(OH)D and first-trimester miscarriages, suggesting vitamin D as a modifiable risk factor for miscarriage. To test this hypothesis, randomized controlled trials should investigate the possible effect of vitamin D supplementation to increase 25(OH)D concentrations in early pregnancy, or before conception, to decrease risk of miscarriage. This trial was registered at clinicaltrials.gov as NCT02434900.

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Section: Methodsmentioning

confidence: 99%

Vitamin D insufficiency is associated with increased risk of first-trimester miscarriage in the Odense Child Cohort

Andersen

Jørgensen

Jensen

et al. 2015

The American Journal of Clinical Nutrition

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“…The study participants were recruited from the Odense Child Cohort and consisted of children born in the municipality of Odense, Denmark, between June 2010 and October 2013 (11). We focused on mothers who had given birth between April 8, 2012 and October 31, 2012 and asked them to get involved in weekly SMS communication by text.…”

Section: Participantsmentioning

confidence: 99%

Using text messaging to obtain weekly data on infant feeding in a Danish birth cohort resulted in high participation rates

Bruun

Wedderkopp

Mølgaard³

et al. 2016

Acta Paediatrica

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“…Participants were better educated, smoked less and were more often of Danish origin than non-participants (Kyhl et al, 2015). As of November 2014, 2,448 singleton children were active members of the cohort.…”

Section: Study Populationmentioning

confidence: 99%

Prenatal exposure to perfluoroalkyl substances and anogenital distance at 3 months of age in a Danish mother-child cohort

Lind

Priskorn

Lassen

et al. 2017

Reproductive Toxicology

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In the Odense child cohort, serum concentrations of perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), and perfluorodecanoic acid (PFDA) were measured in 638 pregnant women. Birth weight, head and abdominal circumferences and gestational age were determined. Anogenital distance (AGD), the distance from the anus to the genital organs, and penile width were measured 3 months after expected date of birth in 511 children. PFOS, PFHxS, PFNA and PFDA were associated with a decreased AGD in girls (p-trend < 0.05) after adjusting for age and weight-for-age standard deviation score. PFOS in the highest quartile was associated with a 2.8 mm (95% confidence intervals -4.5; -1.1) reduction in AGD in girls. No such tendencies were seen in boys. However, a tendency toward increased birth weight in girls and reduced birth weight in boys suggests that sex-dimorphic effects may occur from endocrine disrupting effects of these substances.

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The Odense Child Cohort: Aims, Design, and Cohort Profile

Abstract: The OCC provides material for in-depth analysis of environmental and genetic factors that are important for child health and disease. Registry data from non-participating women and infants are available which ensures a high degree of comparable data.

Cited by 137 publications

References 24 publications

Vitamin D insufficiency is associated with increased risk of first-trimester miscarriage in the Odense Child Cohort

Vitamin D insufficiency is associated with increased risk of first-trimester miscarriage in the Odense Child Cohort

Using text messaging to obtain weekly data on infant feeding in a Danish birth cohort resulted in high participation rates

Prenatal exposure to perfluoroalkyl substances and anogenital distance at 3 months of age in a Danish mother-child cohort

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