The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium)

Thiry, Nancy; Beutels, Philippe; Shkedy, Ziv; Vranckx, R.; Vandermeulen, Corinne; Wielen, Marie Van der; Damme, Pierre Van

doi:10.1007/s00431-002-1053-2

Cited by 49 publications

(34 citation statements)

References 27 publications

(38 reference statements)

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“…In 2007, 96.1% of Spanish women during their fertility period were immune to VZV (22). In Belgium, the prevalence of Anti-VZV IgG among young women was 100% (23). In addition to demographic, climatic, and socioeconomic factors, the performance of the varicella vaccination program in developed countries may partly explain the difference between these findings and our result.…”

Section: Discussioncontrasting

confidence: 74%

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

et al. 2016

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Background and Aims: Varicella-zoster virus (VZV) infection among pregnant women can cause a serious threat to the health of mother and fetus. Varicella is clearly less dangerous for immunized mothers. The aim of this study was to determine the prevalence of VZV antibody among women before marriage. Materials and Methods: This cross-sectional study was conducted on 300 women of childbearing age who referred to Yazd clinic for premarital screening. The enzyme-linked immunosorbent assay (ELISA) technique was performed to detect antibodies against VZV. Demographic characteristics of each participant, including age, educational level, place of residence, family and self-reported history of chickenpox were collected by a questionnaire. Results: Mean age of women under study was 23±5.4 years that 223 participants (73.7%) were seropositive, and 77 cases (25.7%) were seronegative for anti-VZV antibody, while 2 (0.6%) subjects had an equivocal result. A higher immunity ratio (86.4%) was found among older women (33-44 years). Data showed no significant correlation between immunity to VZV and age, educational level, place of residence. A statistically significant association was found between the family history, self-reported history of chickenpox and immunity to VZV. The positive and negative predictive values for self-reported history of chicken pox were 97.1% and 81.1%, respectively. Conclusions: A significant number of women before marriage had no immunity to VZV. They are in risk of getting varicella, which can cause serious complications in mother and fetus. It, therefore, seems necessary to screen women of child-bearing age for anti-VZV antibody. In addition, vaccination against VZV in Iranian women before marriage can be a good recommendation.

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Section: Discussioncontrasting

confidence: 74%

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

et al. 2016

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“…The observed age-specific seroprevalence is shown in the upper panel of Figure 1. Previous similar studies on VZV were reported by Thiry et al (2002) and Nardone et al (2007).…”

Section: Varicella Zoster Virussupporting

confidence: 82%

Modelling distortions in seroprevalence data using change-point fractional polynomials

Hens

Kvitkovičová

Aerts

et al. 2010

Statistical Modelling

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This paper shows how to model seroprevalence data using changepoint fractional polynomials. The inclusion of a change-point in the fractional polynomial framework allows to detect distortions arising from common (often untestable) assumptions made in the estimation of the age-specific prevalence and force of infection from cross sectional data. The method is motivated using seroprevalence data on the parvovirus B19 and the varicella zoster virus in Belgium.

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“…Negative predictive value of the history was 41% (Table 3), low and unreliable, as reported in the literature 30 . By contrast, positive predictive value of previous history of varicella in Xingu National Park was high, 98%, and it could be an efficient and economic measure to avoid vaccination, excluding from the "susceptible" category the individuals who referred previous varicella.…”

Section: Discussionsupporting

confidence: 57%

“…In these countries, indirect immunosorbent assay (ELISA) used to detect IgG VZV antibodies have demonstrated prevalence equal to or higher than 90% 1,9,16,21,27,[30][31] . In Brazil, general surveys have shown a seroprevalence of 85.4% 10 and 94.2% 26 , closer to the pattern observed in temperate countries.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination

Lafer

Moraes-Pinto

Weckx

2005

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples -volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% -86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.

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The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium)

Cited by 49 publications

References 27 publications

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

Modelling distortions in seroprevalence data using change-point fractional polynomials

Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination

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