The Sevilla Powder Tester: A Tool for Characterizing the Physical Properties of Fine Cohesive Powders at Very Small Consolidations

Abstract

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Near-Infrared Spectroscopy for the In-Line Characterization of Powder Voiding Part II: Quantification of Enhanced Flow Properties of Surface Modified Active Pharmaceutical Ingredients

“…The flow behavior of granular materials can be broadly classified into four different flow regimes: plastic behavior, inertial flow, fluidized flow, and entrained flow, determined by particle size, density, and gas flow [17]. However, a single physical model is not capable of explaining the behavior of granular material in all four dynamic regimes.…”

Near-infrared Spectroscopy for the In-line Characterization of Powder Voiding Part I: Development of the Methodology

“…Jenike shear tests evaluate the angle of internal friction of highly consolidated granular materials [3]. The ratio of bulk and tap density has been used as a flow index based on packing geometry and describes percent compressibility [4].…”

Effect of particle size polydispersity on the yield stress of magnetofluidized beds as depending on the magnetic field orientation

“…Thus, the gas flow puts the bed under tension until there comes a point at which the powder breaks at the bottom and Dp falls down abruptly. The tensile yield stress r t at the bottom of the bed can be then estimated as the difference between the maximum pressure drop across the bed (just before the breaking) and the weight per unit area r t ¼ Dp max À W [112,11]. Further increase of the gas velocity gives rise to a state of heterogeneous fluidization, whose main feature is the propagation of the fracture in the upward direction and the development of visible gas bubbles for large gas velocities.…”

“…The setup used in this work for the magnetofluidization experiments was based on the Sevilla Powder Tester (SPT) characterization device described in [112][113][114], which allows automatic control and acquisition. Fig.…”