The significance of allergic contact urticaria to milk in children with cow's milk allergy

Schichter-Konfino, Vered; Almog, Meital; Bamberger, Ellen; Berkowitz, Drora; Kessel, Aharon

doi:10.1111/pai.12375

Cited by 19 publications

(12 citation statements)

References 20 publications

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“…This so-called "finger test" could provide additional confirmation of CMA. 11 Contrary to the results of other studies that showed no significant specificity of abdominal colic, 12e15 we demonstrated this clinical sign to be the most specific for CMA. Although the etiology of abdominal colic is multifactorial, some studies have shown that even without confirmation of CMA, the introduction of partially or extensively hydrolyzed CM leads to improvement in the clinical picture, probably because of the favorable effect of hydrolyzed formula on intestinal motility and digestion.…”

Section: Discussioncontrasting

confidence: 99%

Prognostic accuracy of clinical signs and diagnostic tests in cow's milk allergy in newborns

Nosan

Jakič

Jager

et al. 2017

Pediatrics & Neonatology

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Section: Discussioncontrasting

confidence: 99%

Prognostic accuracy of clinical signs and diagnostic tests in cow's milk allergy in newborns

Nosan

Jakič

Jager

et al. 2017

Pediatrics & Neonatology

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“…Also contact urticaria is typically associated only with IgE-mediated CMA. 86 Upon ingestion of the milk, the smooth muscles in esophagus and stomach can quickly react and cause vomiting, or in the intestine lead to diarrhea (immediate gastrointestinal hypersensitivity). Absorption of milk proteins via the mucosa can occur at any of these time points and potentially lead to systemic reactions, like skin exacerbations (acute urticaria, erythema, angioedema), asthma attacks, and also anaphylactic shock in severely milk allergic patients.…”

Section: Mechanisms Of Ige-mediated Reactions To Cow's Milkmentioning

confidence: 99%

World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - III - Cow's milk allergens and mechanisms triggering immune activation

Jensen¹,

Fiocchi²,

Baars³

et al. 2022

World Allergy Organization Journal

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“…dust mite; house dust mites; cockroach; acacia; mug wort; dog epithelium; cat epithelium; Cytospora; specific Penicillium; hay dust; cotton wool; beef; carp; shrimp; soybean; wheat flour; milk; eggs; red pepper and peanuts).Wheals with a mean diameter at least three millimeters or more than those of the negative control were considered positive reactions. 9,10…”

Section: Laboratory Investigationsmentioning

confidence: 99%

Clinical difference between single subtype and mixed subtype chronic urticaria: A retrospective study

Mao

Yuan

Xiao

et al. 2021

IJDVL

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Background: The subtypes of chronic urticaria share a common clinical expression, but may show differences phenotypically. Meanwhile, two or more different subtypes of chronic urticaria can coexist in any given patient which may involve different phenotypes. Aims: The study aims to compare the two phenotypes in terms of demographics, clinical profile and treatment response. Methods: In this retrospective study, 2678 chronic urticaria patients were divided into the single subtype chronic urticaria group and mixed subtype chronic urticaria group as was appropriate.The differences in the clinical features, possible causes, urticaria activity score of seven days, dermatology life quality index score, laboratory investigations and response to treatments were evaluated among the two groups. Results: An obvious female predominance was detected in chronic urticaria, especially in mixed subtype chronic urticaria patients. Of the 2678 chronic urticaria patients, there were 837(31.25%) mixed subtype chronic urticaria. Chronic spontaneous urticaria combined with symptomatic dermographism was the most common group in the mixed subtype chronic urticaria. Patients with mixed subtype chronic urticaria were more likely to have associated chest tightness/shortness of breath and showed greater urticaria activity. In patients with single subtype chronic urticaria, the positive rate of family history with allergic rhinitis, asthma or urticaria was lower. Based on evaluation of the treatment, control with second-generation antihistamines at licensed doses was achieved in only 38.83% of mixed subtype chronic urticaria patients, compared with 56.32% of patients with single subtype. Limitations: First, this study was a single-center design retrospective study. Second, omalizumab treatment was not included. Third, the differences between different subtypes of mixed subtype chronic urticaria were not discussed in detail. Conclusion: This study showed that mixed subtype chronic urticaria had some distinct features. Comprehensive knowledge about it may help us define effective therapeutic strategies and improve symptom control and the quality of life for chronic urticaria patients.

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The significance of allergic contact urticaria to milk in children with cow's milk allergy

Abstract: CMP contact urticaria exists only in patients with IgE-mediated CMA. A 'finger test' to CMP should be part of the evaluation of CMA patients, and positivity suggests the potential for multiple food allergies, especially to sesame and egg.

Cited by 19 publications

References 20 publications

Prognostic accuracy of clinical signs and diagnostic tests in cow's milk allergy in newborns

Prognostic accuracy of clinical signs and diagnostic tests in cow's milk allergy in newborns

World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - III - Cow's milk allergens and mechanisms triggering immune activation

Clinical difference between single subtype and mixed subtype chronic urticaria: A retrospective study

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