The size of non-hippocampal brain regions varies by season and sex in Richardson’s ground squirrel

Keeley, Robin J.; Burger, Danielle K.; Saucier, Deborah M.; Iwaniuk, Andrew N.

doi:10.1016/j.neuroscience.2014.12.077

Cited by 6 publications

(4 citation statements)

References 124 publications

(196 reference statements)

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“…From literature the values for the rat neocortex volume 78 and the ratio 79 were obtained. Similarly, the squirrel neocortex volume 80 and the ratio 79 sourced from previous literature. Neocortex volume of the agouti was calculated by multiplying the cortical flat-mount area 81 with cortical thickness.…”

Section: Calculation Of the V1/neocortex Ratio And Volumesmentioning

confidence: 99%

Orientation Preference Maps in Microcebus murinus Reveal Size-Invariant Design Principles in Primate Visual Cortex

Zimmermann

Weidinger

et al. 2021

Current Biology

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Section: Calculation Of the V1/neocortex Ratio And Volumesmentioning

confidence: 99%

Orientation Preference Maps in Microcebus murinus Reveal Size-Invariant Design Principles in Primate Visual Cortex

Zimmermann

Weidinger

et al. 2021

Current Biology

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“…Different reports exist dealing with sex influence, mainly related with brain region studied, normalization of the brain size, and methodology, as Keeley et al . report [ 36 ]. Our study shows data variability when different compartments were measured that, in addition to the scarce number of cases studied, resulted in no sex differences, being in accordance with the more exhaustive study of Insausti et al .…”

Section: Discussionmentioning

confidence: 99%

Quantitative Measurements in the Human Hippocampus and Related Areas: Correspondence between Ex-Vivo MRI and Histological Preparations

et al. 2015

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The decrease of volume estimates in different structures of the medial temporal lobe related to memory correlate with the decline of cognitive functions in neurodegenerative diseases. This study presents data on the association between MRI quantitative parameters of medial temporal lobe structures and their quantitative estimate in microscopic examination. Twelve control cases had ex-vivo MRI, and thereafter, the temporal lobe of both hemispheres was sectioned from the pole as far as the level of the splenium of the corpus callosum. Nissl stain was used to establish anatomical boundaries between structures in the medial temporal lobe. The study included morphometrical and stereological estimates of the amygdaloid complex, hippocampus, and temporal horn of the lateral ventricle, as well as different regions of grey and white matter in the temporal lobe. Data showed a close association between morphometric MRI images values and those based on the histological determination of boundaries. Only values in perimeter and circularity of the piamater were different. This correspondence is also revealed by the stereological study, although irregular compartments resulted in a lesser agreement. Neither age (< 65 yr and > 65yr) nor hemisphere had any effect. Our results indicate that ex-vivo MRI is highly associated with quantitative information gathered by histological examination, and these data could be used as structural MRI biomarker in neurodegenerative diseases.

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“…Seasonal changes in cell proliferation have been described in the hypothalamus and thalamus of sheep (Migaud et al, 2011), the olfactory bulb of mice (Walton et al, 2012), and the hippocampus of mice (Burger et al, 2013). Keeley et al (2015) have shown that in the ground squirrel there are seasonal changes in the size of regions that are not directly involved in seasonal breeding state, including certain cortical areas and the superior colliculus. Moreover, these changes are more pronounced in females than males (Keeley et al 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Keeley et al (2015) have shown that in the ground squirrel there are seasonal changes in the size of regions that are not directly involved in seasonal breeding state, including certain cortical areas and the superior colliculus. Moreover, these changes are more pronounced in females than males (Keeley et al 2015). The hippocampus of the ground squirrel also undergoes seasonal changes in size, and these changes are different in males and females (Burger et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Seasonal variations in auditory processing in the inferior colliculus of Eptesicus fuscus

et al. 2016

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Eptesicus fuscus is typical of temperate zone bats in that both sexes undergo marked seasonal changes in behavior, endocrine status, and reproductive status. Acoustic communication plays a key role in many seasonal behaviors. For example, males emit specialized vocalizations during mating in the fall, and females use different specialized vocalizations to communicate with infants in late spring. Bats of both sexes use echolocation for foraging during times of activity, but engage in little sound-directed behavior during torpor and hibernation in winter. Auditory processing might be expected to reflect these marked seasonal changes. To explore the possibility that seasonal changes in hormonal status could drive functional plasticity in the central auditory system, we examined responses of single neurons in the inferior colliculus throughout the year. The average first-spike latency in females varied seasonally, almost doubling in spring compared to other times of year. First-spike latencies in males remained relatively stable throughout the year. Latency jitter for both sexes was higher in winter and spring than in summer or fall. Females had more burst responders than other discharge patterns throughout the year whereas males had more transient responders at all times of year except fall, when burst responses were the predominant type. The percentage of simple discharge patterns (sustained and transient) was higher in males than females in the spring and higher in females than males in the fall. In females, the percentage of shortpass duration-tuned neurons doubled in summer and remained elevated through fall and early winter. In males, the percentage of shortpass duration-tuned cells increased in spring and the percentage of bandpass duration-tuned cells doubled in the fall. These findings suggest that there are clear seasonal changes in basic response characteristics of midbrain auditory neurons in Eptesicus, especially in temporal response properties and duration sensitivity. Moreover, the pattern of changes is different in males and females, suggesting that hormone-driven plasticity adjusts central auditory processing to fit the characteristics of vocalizations specific to seasonal behavioral patterns.

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The size of non-hippocampal brain regions varies by season and sex in Richardson’s ground squirrel

Cited by 6 publications

References 124 publications

Orientation Preference Maps in Microcebus murinus Reveal Size-Invariant Design Principles in Primate Visual Cortex

Orientation Preference Maps in Microcebus murinus Reveal Size-Invariant Design Principles in Primate Visual Cortex

Quantitative Measurements in the Human Hippocampus and Related Areas: Correspondence between Ex-Vivo MRI and Histological Preparations

Seasonal variations in auditory processing in the inferior colliculus of Eptesicus fuscus

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