The skin in disseminated intravascular coagulation.

Robboy, Stanley J.; Mihm, Martín C.; Colman, Robert W.; Minna, John D.

doi:10.1111/j.1365-2133.1973.tb07538.x

Cited by 84 publications

(28 citation statements)

References 5 publications

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“…The cutaneous findings include petechiae, macular or palpable purpura, hemorrhagic bullae, subcutaneous hematomas, and bleeding from areas of trauma, such as venipuncture sites or surgical wounds. 88 Acrocyanosis in DIC is a gun-metal gray to purplish, sharply demarcated and symmetrical discoloration of the tips of the fingers or toes that may progress to gangrene. A distinctive finding, purpura fulminans, tends to occur with infections and consists of an extensive confluent purpura of explosive onset, frequently associated with hemorrhagic bullae and focal gangrene (Fig 10).…”

Section: Disseminated Intravascular Coagulationmentioning

confidence: 99%

Blue (or purple) toe syndrome

Hirschmann¹,

Raugi²

2009

Journal of the American Academy of Dermatology

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Section: Disseminated Intravascular Coagulationmentioning

confidence: 99%

Blue (or purple) toe syndrome

Hirschmann¹,

Raugi²

2009

Journal of the American Academy of Dermatology

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“…Once this process starts, changes in the patient’s status occur rapidly and require intense monitoring with subsequent changes in therapy as indicated [2]. The classic cutaneous manifestations of DIC present as skin wounds such as bruising, contusions, petechiae, purpura, acral cyanosis, hemorrhagic bullae, purpura fulminans, subcutaneous dissecting hematomata, or bleeding from wound or venipuncture sites [3]. …”

Section: Introductionmentioning

confidence: 99%

Topical allogeneic platelet-rich plasma treatment for a massive cutaneous lesion induced by disseminated intravascular coagulation in a toy breed dog

et al. 2015

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A 2-year-old intact female miniature Pinscher weighing 1.7 kg with a body condition score of 2/5 was presented for acute vomiting, lethargy for 2 days, and large petechial skin lesions on the hip region including the tail. Acute pancreatitis was diagnosed by clinical signs, strong positive cPLI test, laboratory test and ultrasound appearance. While the clinical signs associated with acute pancreatitis had improved in 3–5 days, lesion of petechial appeared on the left hip region 7 days after the presentation, with a fast progression into a necrotic tissue along the left side hip. Allogenic platelet rich plasma (PRP) with Weibrich and Kleis method was administered to promote skin healing and regeneration. Gradual and complete improvement in the dog’s wound lesions was noted approximately 1 month after applying allogeneic topical PRP. In this case report, allogeneic PRP was applied to a large regional cutaneous defect caused by coagulopathy induced by acute pancreatitis. Topical application of PRP in this case was unique in that allogeneic PRP was used instead of autologous PRP for the first time in cutaneous soft-tissue wound management in the veterinary medical field.

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“…]. Pathology studies have supported the central role of intravascular clotting in this process [42,43], although occasional studies have not documented diffuse thrombosis [19].…”

Section: Consumptive Thrombocytopenianonimmunologicalmentioning

confidence: 99%

Thrombocytopenia in the Intensive Care Unit Setting

Wittels

Siegel

Mazur

1990

J Intensive Care Med

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Thrombocytopenia is a commonly encountered labora tory abnormality in the intensive care unit setting. Al though moderate degrees of thrombocytopenia may be dismissed as clinically trivial, severe thrombocytopenia can have catastrophic consequences. This review di vides the potential pathogenesis of thrombocytopenia into three pathophysiological categories: (1) produc tive, (2) consumptive, and (3) distributional. The im portant etiologies and appropriate therapies for throm bocytopenia in each of these categories are discussed. We have attempted to emphasize the underlying patho genic mechanisms as well as highlight the diagnostic dilemmas likely to be faced by intensive care unit physi cians. Although this review stresses those thrombocyto penic disorders most likely to be encountered in the intensive care unit, chronic etiologies of thrombocy topenia are also discussed because preexistent throm bocytopenia will further complicate the care of any acutely ill intensive care unit patient.

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The skin in disseminated intravascular coagulation.

Cited by 84 publications

References 5 publications

Blue (or purple) toe syndrome

Blue (or purple) toe syndrome

Topical allogeneic platelet-rich plasma treatment for a massive cutaneous lesion induced by disseminated intravascular coagulation in a toy breed dog

Thrombocytopenia in the Intensive Care Unit Setting

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