The Smaller Halogenated Aliphatic Hydrocarbons

Chenoweth, and M B; Hake, C L

doi:10.1146/annurev.pa.02.040162.002051

Cited by 77 publications

(23 citation statements)

References 97 publications

(99 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Being cytoplasamic in location the damage marker enzymes like, AST, ALT and ALP are released in serum [25,26]. These carotenoids show their protective activity by impairment of CCl 4 -mediated lipid peroxidation, either by decrease in production of free radical derivatives or by the antioxidant activity of these compounds.…”

Section: Discussionmentioning

confidence: 99%

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Murthy

Rajesha

Vanitha

et al. 2005

Hepatology Research

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Murthy

Rajesha

Vanitha

et al. 2005

Hepatology Research

View full text Add to dashboard Cite

“…In acute liver damage, increased levels of serum transaminases GPT and GOT, a sensitive index of hepatic damage is present in CCI4 damage (Chenoweth and Hake, 1962). Hyperbilirubinaemia is also one of the most useful clues to the severity of necrosis (Zimmerman, 1973).…”

Section: Discussionmentioning

confidence: 99%

Hepatoprotective studies of a fraction from the fruits of Terminalia belerica roxb. On experimental liver injury in rodents

Anand

Singh

Saxena

et al. 1994

Phytotherapy Research

View full text Add to dashboard Cite

The effects of an orally administered fraction (TB5) from the fruits of Tenninalia belerica in experimental liver injury induced by carbon tetrachloride (CC4) were studied. Hexobarbitone-induced sleep, zoxazolamineinduced paralysis, transaminases, bilirubin, total protein in serum and microsomal lipid peroxidation and triglycerides in liver were used as indices of liver injury.A significant hepatoprotective effect was observed as evident from shortened hexobarbitone 'sleep time' and zoxazolamine 'paralysis time' when compared with CCI, alone. Pre-and post-treatment of TB5 reduced, in a dose dependent manner, the elevated levels of serum tranaminases and bilirubin in rats, thus demonstrating its effect both as a prophylactic and curative. Its protective effects on microsomal lipid peroxidation and triglycerides in liver suggest a restorative effect in the process of CCC-induced liver damage. TB5 did not show any signs of toxicity up to oral doses of 3.2 g/kg in mice.

show abstract

“…This makes it difficult to be excreted from the body. Fat soluble chemicals have a high affinity for fat tissues and cell membranes and are thus well distributed throughout the body (Chenoweth and Hake, 1962). The biochemical mechanisms involved in the development of CCl 4 hepatotoxicity have long been investigated.…”

Section: Discussionmentioning

confidence: 99%

Histological and biochemical studies on the effect of tetrodotoxin extracted from Puffer fish (Lagocephalus sceleratus) against carbon tetrachloride induced hepatotoxicity in albino mice.

Khalil¹,

Swelim²,

Zaky³

2018

Egypt. J. of Aquatic Biolo. and Fish.

View full text Add to dashboard Cite

The Smaller Halogenated Aliphatic Hydrocarbons

Cited by 77 publications

References 97 publications

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Protective effect of —A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats

Hepatoprotective studies of a fraction from the fruits of Terminalia belerica roxb. On experimental liver injury in rodents

Histological and biochemical studies on the effect of tetrodotoxin extracted from Puffer fish (Lagocephalus sceleratus) against carbon tetrachloride induced hepatotoxicity in albino mice.

Contact Info

Product

Resources

About