The socioeconomic variables influence in the alpha-tocopherol concentration of the maternal serum

Ribeiro, Karla Danielly da Silva; Weigert, Luana; Andrade, Talita Soares de; Lima, Amanda Pereira; Medeiros, Jeane Franco Pires; Lima, Mayara Santa Rosa; Bezerra, Danielle Soares; Osório, Mônica Maria; Domenstein, Roberto

doi:10.1590/1806-930420170001000010

Cited by 1 publication

(4 citation statements)

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“…A sensitivity analysis using the leave-one-out method was conducted but was unable to reduce the heterogeneity (89%-96%), and the overall prevalence ranged from 4% to 8% (see supplementary data: Table S3, available in OSF: https://osf.io/j9qmh/). 20 In this analysis, withdrawal of the study by Ribeiro et al, 34 which was the only study that did not include breastfeeding women, resulted in a prevalence of vitamin E deficiency of 7% (95% CI 5%-8%), with I 2 of 96%. The studies with most influence on the variations were those of de Azeredo et al, 14 on teenager breastfeeding, and Clemente et al, 31 on breastfeeding in general.…”

Section: Prevalence Analysismentioning

confidence: 96%

“…Furthermore, most of the studies did not report mean BMI, ethnicity, educational level or per capita income. Only five studies 11,[31][32][33][34][35] reported on the participants' educational level, and showed that the majority had low levels (data not shown). Six studies 11,12,[32][33][34][35][36] reported on per capita income and showed that the majority of the participants had monthly per capita income of less than one minimum wage (data not shown).…”

Section: Characteristics Of Studies and Participantsmentioning

confidence: 99%

“…Only five studies 11,[31][32][33][34][35] reported on the participants' educational level, and showed that the majority had low levels (data not shown). Six studies 11,12,[32][33][34][35][36] reported on per capita income and showed that the majority of the participants had monthly per capita income of less than one minimum wage (data not shown). The main characteristics of the participants are described in Table 1.…”

Section: Characteristics Of Studies and Participantsmentioning

confidence: 99%

“…Eleven studies reported on the prevalence of deficiency or insufficiency of vitamin E. 12,14,[29][30][31][33][34][35][36][37][38][39] Different cutoffs for alpha-tocopherol in plasma were used, but a meta-analysis with three subgroups could be conducted. Machado et al 12 and Monteiro et al 30 were not included in any vitamin E meta-analysis because their cutoffs of < 9.7 mmol/l, 9.7-16.2 mmol/l and < 7 mmol/l were not used in any other study.…”

Section: Prevalence Analysismentioning

confidence: 99%

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Deficiency of vitamins C and E in women of childbearing age in Brazil: a systematic review and meta-analysis

et al. 2021

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BACKGROUND: Despite the several options available for supplements containing vitamins C and E, evidence regarding the prevalence of deficiency or insufficiency of these vitamins is weak. OBJECTIVES: To estimate the prevalence of deficiency or insufficiency of vitamins C and E and associated factors among women of childbearing age, in Brazil. DESIGN AND SETTING: Systematic review and meta-analysis conducted at a Brazilian public university. METHODS: A search from index inception until May 2020 was conducted. Meta-analyses were performed using inverse variance for fixed models, with summary proportions calculation using Freeman-Tukey double arcsine (base case). Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. RESULTS: Our review identified 12 studies, comprising 1,316 participants, especially breastfeeding women. There was at least one quality weakness in all studies, mainly regarding sampling method (i.e. convenience sampling) and small sample size. The prevalence of vitamin C deficiency ranged from 0% to 40%. Only vitamin E deficiency was synthetized in meta-analyses, with mean prevalences of 6% regardless of the alpha-tocopherol cutoff in plasma, and 5% and 16% for cutoffs of < 1.6-12.0 mmol/l and < 16.2 mmol/l, respectively. The cumulative meta-analysis suggested that a trend to lower prevalence of vitamin E deficiency occurred in recent studies. CONCLUSIONS: Although the studies identified in this systematic review had poor methodological and reporting quality, mild-moderate vitamin C and E deficiencies were identified, especially in breastfeeding women. Thus, designing and implementing policies does not seem to be a priority, because the need has not been properly dimensioned among women of childbearing age in Brazil. REGISTRATION NUMBER IN PROSPERO: CRD42020221605.

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Section: Prevalence Analysismentioning

confidence: 96%