The solubility of oxygen in aqueous fluorocarbon emulsions

Sharts, Clay M.; Reese, H.; Ginsberg, Kenneth A.; Multer, Frances K.; Nielson, Margot D.; Greenburg, A. Gerson; Peskin, Gerald W.; Long, David M.

doi:10.1016/s0022-1139(00)81622-x

Cited by 25 publications

(12 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These unusual physicochemical properties explain the ability of PFCs to dissolve oxygen, carbon-dioxide and nitrogen. Sharts and Reese 24 have shown that in emulsified linear perfluorocarbons, the number of fluorines directly correlates to its ability to solubilize oxygen. The first biological applications of PFCs exploited the high oxygen solubility.…”

Section: Physicochemical Propertiesmentioning

confidence: 99%

See 1 more Smart Citation

Fluorine‐containing nanoemulsions for MRI cell tracking

Janjić

Ahrens

2009

WIREs Nanomed Nanobiotechnol

184

285

View full text Add to dashboard Cite

In this article we review the chemistry and nanoemulsion formulation of perfluorocarbons used for in vivo 19F MRI cell tracking. In this application, cells of interest are labeled in culture using a perfluorocarbon nanoemulsion. Labeled cells are introduced into a subject and tracked using 19F MRI or NMR spectroscopy. In the same imaging session, a high-resolution, conventional (1H) image can be used to place the 19F-labeled cells into anatomical context. Perfluorocarbon-based 19F cell tracking is a useful technology because of the high specificity for labeled cells, ability to quantify cell accumulations, and biocompatibility. This technology can be widely applied to studies of inflammation, cellular regenerative medicine, and immunotherapy.

show abstract

Section: Physicochemical Propertiesmentioning

confidence: 99%

“…One of earliest reported PFC nanoemulsion surfactants was Pluronic F68 TM (BASF). 24 This molecule is a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock non-ionic copolymer that is FDA approved for human use. F68 stabilizes the PFC oil droplets in aqueous phase mostly by steric effects.…”

Section: Non-ionic Surfactantsmentioning

confidence: 99%

Fluorine‐containing nanoemulsions for MRI cell tracking

Janjić

Ahrens

2009

WIREs Nanomed Nanobiotechnol

184

285

View full text Add to dashboard Cite

show abstract

“…The new ionic liquid 1-n-butyl-3-methylimidazolium pentadecafluorooctanoate (BMI.COO(CF 2 ) 6 CF 3 ) was synthesized to check whether the amount of oxygen dissolved in fluorinated ionic liquids increases as it happens with the fluorinated hydrocarbons, 30 and enables a higher conversion.…”

Section: Resultsmentioning

confidence: 99%

Aerobic, catalytic oxidation of alcohols in ionic liquids

Souza

Dupont

Dullius

2006

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

Um sistema catalítico simples e eficiente, baseado em RuCl 3 imobilizado em líquidos iônicos, foi desenvolvido para oxidar álcoois a aldeídos e cetonas sob condições brandas. Um novo líquido iônico fluorado, pentadecafluorooctanoato de 1-n-butil-3-metilimidazólio, foi sintetizado e demonstrou melhor desempenho que os demais líquidos iônicos empregados. Além disso, este sistema catalítico utiliza oxigênio molecular como agente oxidante, produzindo somente água como subproduto.An efficient and simple catalytic system based on RuCl 3 dissolved in ionic liquids has been developed for the oxidation of alcohols into aldehydes and ketones under mild conditions. A new fluorinated ionic liquid, 1-n-butyl-3-methylimidazolium pentadecafluorooctanoate, was synthesized and demonstrated better performance that the other ionic liquids employed. Moreover this catalytic system utilizes molecular oxygen as an oxidizing agent, producing water as the only by-product.

show abstract

“…Since the solvent was reported to have a crucial role in the TPAP-aerobic oxidation of alcohols [9], we explored either classical media such as acetonitrile and dichloromethane, or fluorous solvents (namely trifluoroethanol (TFE), trifluorotoluene (BTF) and hexafluoroisopropanol (HFIP)). These latter, as a consequence of their low tendency to undergo van der Waals interactions, are able to solubilize gases very well and are immiscible with many organic solvents at room temperature [15]. Recently, fluorinated alcohols were used with optimal results in the epoxidation of alkenes [16].…”

Section: Methodsmentioning

confidence: 99%