The Source of Recurrent Bacteremia Identified by Trans-esophageal Echocardiography

Porkolab, Frederick L.; Weinbaum, David L.; Lerberg, David B.; Phillips, John C.

doi:10.7326/0003-4819-112-8-628

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…Several studies have shown that hydroxychloroquine positively affects insulin and glucose metabolism. [ 4 7 8 10 11 12 13 ] In fact, the highlighted point of the present study was the effects of hydroxychloroquine on glucose control in the prediabetes, state independent of its effect on body weight and composition as well as on the lipid profile. In fact, the hypoglycemic effect of hydroxychloroquine has been identified as its potential side-effect, but because of no another concomitant effects on other metabolic components and body organs, this effect can be beneficially used for controlling glucose and also for progression of prediabetes to diabetes state.…”

Section: Discussionmentioning

confidence: 72%

“…[ 6 ] Moreover, hydroxychloroquine can inhibit inflammatory biomarkers as well as regulate the level of lipid profile, leading to a reduced risk of diabetes mellitus. [ 6 7 ] Based on the previous studies,[ 8 9 ] it seems likely that hydroxychloroquine can improve most underlying coronary risk factors; however, the exact effects of hydroxychloroquine on blood glucose and insulin resistance among the Iranian population has not been discussed yet. The current study aimed to assess the effects of hydroxychloroquine on blood glucose control status as well as lipid profile and inflammatory biomarkers in prediabetic patients.…”

Section: Introductionmentioning

confidence: 99%

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The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

et al. 2016

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Background:Hydroxychloroquine can improve most underlying coronary risk factors; however, there are a few studies on the effects of hydroxychloroquine on blood glucose and insulin resistance. The current study aimed to assess the effects of hydroxychloroquine on blood glucose control status as well as on level of lipid profile and inflammatory biomarkers in prediabetic patients.Materials and Methods:In a randomized, double-blinded, controlled trial, 39 consecutive patients who were suffering from prediabetes and were referred to the Isfahan Endocrinology Center in January 2013 were randomly assigned to receive hydroxychloroquine (6.5 mg/kg/day) (n = 20) or placebo (n = 19) for 12 weeks. The biomarker indices and anthropometric parameters were tested before and after completion of treatment.Results:In both groups of patients receiving hydroxychloroquine and placebo, except for serum level of insulin that was significantly elevated after treatment by hydroxychloroquine, the changes in other parameters remained insignificant. Both groups experienced increase of insulin level, but this change was considerably higher in those groups receiving hydroxychloroquine. The group receiving hydroxychloroquine experienced reduction of glucose at 60 min of Oral Glucose Tolerance Test (OGTT) test after intervention, while the placebo group experienced increase of blood glucose at the same time.Conclusion:The use of hydroxychloroquine may increase the serum insulin level in patients with prediabetic states who are at risk of developing diabetes mellitus.

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Section: Discussionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

et al. 2016

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Чапаева

Nepomnyashchikh

Айдагулова

et al. 2001

Bulletin of Experimental Biology and Medicine

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Degeneration and atrophy of the epidermis, disorganization of the connective tissue, focal atrophy of skeletal myocytes, and diffuse vasculopathy are the main pathomorphological signs found in musculocutaneous bioptates during the antiphospholipid syndrome associated with systemic lupus erythematosus. The major morphogenetic disorder is alteration of microvascular endotheliocytes accompanied by the formation of concentric perivascular mononuclear infiltrates.

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Endocarditis Complicating Parenteral Nutrition: The Value of Repeated Echocardiography

Leinhardt¹,

Ragavan²,

O’Hanrahan³

et al. 1992

J Parenter Enteral Nutr

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Cardiac complications of parenteral nutrition are well recognized but the diagnosis of such complications may be difficult. Two-dimensional echocardiography has been shown to be of value in establishing the diagnosis of valvular vegetations and right atrial thrombus. We describe two patients who developed endocarditis while receiving parenteral nutrition via central venous catheters. In both cases initial echocardiography was normal and the tricuspid valvular vegetations were only picked up after one or more additional echocardiograms. This highlights the necessity for repeated echocardiography in patients receiving parenteral nutrition in whom infective central venous catheter complications fail to resolve quickly after appropriate treatment.

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The Source of Recurrent Bacteremia Identified by Trans-esophageal Echocardiography

Cited by 3 publications

References 6 publications

The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

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Endocarditis Complicating Parenteral Nutrition: The Value of Repeated Echocardiography

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