The spatiotemporal distribution of human brucellosis in mainland China from 2007-2016

Abstract

Background: Despite the considerable efforts made to address the issue of brucellosis worldwide, its prevalence in dairy products continues to be difficult to estimate and represents a key public health issue around the world today. The aim of the present study was to better understand the epidemiology of this disease in mainland China. We set out to investigate the yearly spatial distribution and possible hotspots of the disease. Methods: Human brucellosis data from mainland China between 2007 and 2016 were collected from the China Information System for Disease Control and Prevention. A geographic information system ArcGIS10.3 (ESRI, Redlands) was used to identify potential changes in the spatial and temporal distribution of human brucellosis in mainland China during the study period. These distributions were evaluated using three-dimensional trend analysis and spatial autocorrelation analyse. A gravity-center was used to analyse the migration track of human brucellosis. Results: A total of 399,578 cases of human brucellosis were reported during the 10-year study period. The monthly incidence of brucellosis in China demonstrates clear seasonality. Spring and summer are the peak seasons, while May is the peak month for brucellosis. Three-dimensional trend analysis suggests that brucellosis is on the rise from south to north, and that the epidemic situation in northern China is more severe. Between 2007 and 2016, the overall migration distance of the brucellosis incidence gravity-center was 906.43 km, and the direction was southwest. However, the overall gravity center of brucellosis was still in the northern part of China. In the global autocorrelation analysis, brucellosis in China demonstrated a non-random distribution between 2013 and 2014, with spatial autocorrelation (Z > 1.96, P < 0.05) and a clustering trend, while no clustering trend was found from 2007 to 2012 or from 2015 to 2016. In the local autocorrelation analysis, a Low-Low cluster phenomenon was found in the south of China in 2013 and 2014. Conclusion: Human brucellosis remains a widespread challenge, particularly in northern China. The hotspots highlight potential high-risk areas which may require special plans and resources for monitoring and controlling the disease.

Epidemiologically characteristics of human brucellosis and antimicrobial susceptibility pattern of Brucella melitensis in Hinggan League of the Inner Mongolia Autonomous Region, China

“…A high morbidity level of brucellosis in humans and animals has been found in some regions of China [5]. Although brucellosis is mainly an animal disease, globally, more than 500 000 human cases are reported each year [6].…”

Spatial Effect of Ecological Environmental Factors on Mumps in China during 2014–2018

“…The x, y, and z axes of the geometric centre represent the longitude, latitude, and mumps morbidity of the 31 provinces, respectively. In the regression model, the longitude from east to west and the latitude from south to north are independent variables, and the incidence is the dependent variable [ 21 ].…”

“…Spatial econometric models have been widely used in tuberculosis, hand, foot and mouth disease (HFMD), AIDS and other infectious diseases [ 19 , 20 , 21 , 22 ], but there is still a knowledge gap in the study of mumps. Therefore, this paper aims to use spatial autocorrelation analysis to discover the clustering pattern of mumps and then further detect the spatial association and spillover effect of mumps with meteorological conditions, pollutants, health resources, and economic and social factors by using the Spatial Durbin Panel Model (SDPM) in the spatial econometric models.…”

An overview of human brucellosis: a neglected zoonotic disease in livestock

“…Relatively less incidence of human brucellosis is reported in developed countries in comparison with developing countries (Khurana et al, 2021). The incidence of human brucellosis in China had been increased from 1.41 to 4.22 per 100,000 people between 2005-2014 (Liang et al, 2020). The incidence of brucellosis was 28-160 per 100, 000 person-years in Ethiopia (Tadesse, 2016).…”