The Spectral Displacement Technique for Determining the Binding Constants of β-Cyclodextrin – Alkyltrimethylammonium Inclusion Complexes

Tutaj, B.; Kasprzyk, Anna; Czapkiewicz, Jan

doi:10.1023/b:jiph.0000011783.40427.56

Cited by 23 publications

(10 citation statements)

References 32 publications

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“…The use of spectrophotometric techniques to follow and quantify the complexation between CD and a surfactant depends on the use of a UV, visible or fluorescent sensitive probe [172][173][174][175][176][177][178][179][180]. In order to obtain thermodynamic parameters with a satisfactory accuracy it is necessary to choose a probe that exhibits a large absorbance or emission intensity that changes upon the addition of a small amount of CD to a surfactant solution; this implies that the association constant of CD:probe cannot be too low [181,182].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

The formation of host–guest complexes between surfactants and cyclodextrins

Valente

Söderman

2014

Advances in Colloid and Interface Science

184

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Cyclodextrins are able to act as host molecules in supramolecular chemistry with applications ranging from pharmaceutics to detergency. Among guest molecules surfactants play an important role with both fundamental and practical applications. The formation of cyclodextrin/surfactant host-guest compounds leads to an increase in the critical micelle concentration and in the solubility of surfactants. The possibility of changing the balance between several intermolecular forces, and thus allowing the study of, e.g., dehydration and steric hindrance effects upon association, makes surfactants ideal guest molecules for fundamental studies. Therefore, these systems allow for obtaining a deep insight into the host-guest association mechanism. In this paper, we review the influence on the thermodynamic properties of CD-surfactant association by highlighting the effect of different surfactant architectures (single tail, double-tailed, gemini and bolaform), with special emphasis on cationic surfactants. This is complemented with an assessment of the most common analytical techniques used to follow the association process. The applied methods for computation of the association stoichiometry and stability constants are also reviewed and discussed; this is an important point since there are significant discrepancies and scattered data for similar systems in the literature.In general, the surfactant-cyclodextrin association is treated without reference to the kinetics of the process. However, there are several examples where the kinetics of the process can be investigated, in particular those where volumes of the CD cavity and surfactant (either the tail or in special cases the head group) are similar in magnitude.This will also be critically reviewed.

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Section: Accepted Manuscriptmentioning

confidence: 99%

The formation of host–guest complexes between surfactants and cyclodextrins

Valente

Söderman

2014

Advances in Colloid and Interface Science

184

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“…Previous observations [12] have shown that achievement to maximum refolding yields, for various detergents, requires different minimum number of ␤-CD equivalents. In addition, the association constants for formation of the 1:1 complex between ␤-CD and the anionic/cationic detergents inferred from NMR [22], surface tension [23], ultra filtration [24] and spectral displacement [25] studies indicated that the longer the hydrocarbon chain of the surfactant, the larger is the association constant. The quoted association constants for some of ␤-CD-surfactant complexes are in the following order: CTAB > TTAB > STS > SDS.…”

Section: Kinetics Of Assisted Ca Refoldingmentioning

confidence: 99%

Fluorimetric study of the artificial chaperone-assisted renaturation of carbonic anhydrase: A kinetic analysis

Khodarahmi

Yazdanparast

2005

International Journal of Biological Macromolecules

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“…10 Furthermore, we have demonstrated that these compounds and methylated CDs could be used separately to stabilize metal NPs in water. Our attention was focused on inclusion complexes formed between CD and ammonium salts bearing a long alkyl chain as it is well known that these compounds can strongly interact with b-CD derivatives.…”

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confidence: 96%