The spectrum of haemoglobin variants in two scheduled tribes of Sundargarh district in north-western Orissa, India

Abstract

Isolates of the Bhuyan and Kharia tribes show intra-group variations in prevalence of haemoglobin variants due to founder effect, genetic drift, and the practice of inbreeding in varied geographical and ecological niches in the Sundargarh district of Orissa.

Genetic diversity of hemoglobinopathies, G6PD deficiency, and ABO and Rhesus blood groups in two isolates of a primitive Kharia Tribe in Sundargarh District of Northwestern Orissa, India

“…These two sects of Kharia tribe show the evolutionary trend of the founder effect and/or genetic drift as reported among other populations (Balgir and Sharma 1988). These findings get further support from our earlier studies Balgir 2005a) conducted on this community.…”

“…The tribe, although originally belonged to one ethnic stock, but now divided into three social groups, namely, the Hill Kharia (Pahari or Paudi), Dudh (Pure) Kharia (converted Christian), and Dhelki (Late Comer) Kharia (Hinduised), and are distinguished from each other on the basis of three grades of primitive culture in the state of Orissa (Balgir 2005a). The Hill Kharia, the primitive and backward section, represents the hunting and food gathering stage of economic life along with the practice of primitive culture and rudimentary shifting cultivation.…”

Hematological profile of twenty-nine tribal compound cases of hemoglobinopathies and G-6-PD deficiency in rural Orissa

“…It was observed that the frequency of different hemoglobinopathies and G-6-PD deficiency was very high, being 9.8 and 17.0, and 13.3 and 24.9, respectively in the Bhuyan and Kharia tribal communities. [28,29] Since they are endogamous people practicing clan exogamy and area endogamy, the chances of getting these two defects together in an individual is equally high as tribal endogamy leads to increased homozygosity for recessively inherited disorders in malaria endemic populations. High incidence of G-6-PD deficiency has been reported in areas of the Central Eastern India [28] where the different hemoglobinopathies, i.e.…”

Sickle cell disease status among school adolescents and their tribal community in South Gujarat

“…Sahu T et al 6 has reported Raita, Sabar, Beera, Mandal, etc tribal community in their study in south Orissa. Balgir R S et al 7 has reported sickle cell disease in Bhuyan and Kharia tribes of north-western Orissa.…”